ID Q9ZW89_ARATH Unreviewed; 453 AA.
AC Q9ZW89;
DT 01-MAY-1999, integrated into UniProtKB/TrEMBL.
DT 01-MAY-1999, sequence version 1.
DT 27-MAR-2024, entry version 165.
DE SubName: Full=F5A8.9 protein {ECO:0000313|EMBL:AAD10663.1};
DE SubName: Full=Zinc finger (C3HC4-type RING finger) family protein / BRCT domain-containing protein {ECO:0000313|EMBL:AEE34609.1};
GN OrderedLocusNames=At1g67180 {ECO:0000313|EMBL:AEE34609.1};
GN ORFNames=F5A8.9 {ECO:0000313|EMBL:AAD10663.1}, F5A8_9
GN {ECO:0000313|EMBL:AEE34609.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AAD10663.1};
RN [1] {ECO:0000313|EMBL:AAD10663.1}
RP NUCLEOTIDE SEQUENCE.
RA Federspiel N.A., Palm C.J., Conway A.B., Kurtz D.B., Conway A.R., Au M.,
RA Araujo R., Buehler E., Dewar K., Feng J., Kim C., Li Y., Oji O.,
RA Osborne B.I., Shinn P., Sun H., Toriumi M., Vysotskaia V.S., Yu G.,
RA Ecker J., Theologis A., Davis R.W.;
RL Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEE34609.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3] {ECO:0000313|EMBL:AEE34609.1}
RP NUCLEOTIDE SEQUENCE.
RG TAIR;
RA Swarbreck D., Lamesch P., Wilks C., Huala E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AEE34609.1}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S.,
RA Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AC004146; AAD10663.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34609.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM59700.1; -; Genomic_DNA.
DR PIR; G96695; G96695.
DR RefSeq; NP_001322040.1; NM_001334277.1.
DR RefSeq; NP_176889.1; NM_105388.3.
DR AlphaFoldDB; Q9ZW89; -.
DR SMR; Q9ZW89; -.
DR STRING; 3702.Q9ZW89; -.
DR PaxDb; 3702-AT1G67180-1; -.
DR EnsemblPlants; AT1G67180.1; AT1G67180.1; AT1G67180.
DR EnsemblPlants; AT1G67180.2; AT1G67180.2; AT1G67180.
DR GeneID; 843038; -.
DR Gramene; AT1G67180.1; AT1G67180.1; AT1G67180.
DR Gramene; AT1G67180.2; AT1G67180.2; AT1G67180.
DR KEGG; ath:AT1G67180; -.
DR TAIR; AT1G67180; -.
DR eggNOG; KOG0825; Eukaryota.
DR eggNOG; KOG2043; Eukaryota.
DR HOGENOM; CLU_024969_0_0_1; -.
DR OMA; WADHMAS; -.
DR OrthoDB; 2428800at2759; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9ZW89; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0032183; F:SUMO binding; IPI:TAIR.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR47776; F5A8.9 PROTEIN; 1.
DR PANTHER; PTHR47776:SF2; RING-TYPE E3 UBIQUITIN TRANSFERASE BRCA1; 1.
DR Pfam; PF12738; PTCB-BRCT; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00292; BRCT; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 1..84
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 300..345
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 148..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 270..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..219
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 453 AA; 51930 MW; 03BA1AF40C45D976 CRC64;
MENVVATVSG YHGSDRFKLI KLISHSGASY VGAMSRSITH LVCWKFEGKK YDLAKKFGTV
VVNHRWVEEC VKEGRRVSET PYMFDSGEEV GPLMIELPAV SEEAKVTKKV NKASETFDKY
FSNGGENRSG STSELATWME KNVEANRHSV RLRTKRPSSI LENKENSGVA ESSRKGKKRV
VKQRSYRNLI DLESDEESDN NHHDNSDENQ NETQDHREPA DENVRGFVFE QGETSALRHP
GDLATPNWDV DEIEESENWS HSAVFKRPRS FSPEIKPQDD DESTREETEA TEKAPAQVSC
IICWTEFSSS RGILPCGHRF CYSCIQKWAD RLVSERKKTT CPLCKSNFIT ITKIEDADSS
DQKIYSQTVP DLSSTNNILV VLPEEEEQRQ TLNPLTRASG CSRCYLTEPE ELLIRCHLCN
FRRIHSYCLD PYLLPWTCNH CNDLQMMYHR RNY
//
