ID R0H523_9BRAS Unreviewed; 325 AA.
AC R0H523;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
DE Flags: Fragment;
GN ORFNames=CARUB_v10017639mg {ECO:0000313|EMBL:EOA24389.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA24389.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|RuleBase:RU004475}.
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DR EMBL; KB870809; EOA24389.1; -; Genomic_DNA.
DR RefSeq; XP_006291491.1; XM_006291429.1.
DR AlphaFoldDB; R0H523; -.
DR STRING; 81985.R0H523; -.
DR GeneID; 17886940; -.
DR KEGG; crb:17886940; -.
DR eggNOG; KOG1502; Eukaryota.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF483; CINNAMOYL COA REDUCTASE-LIKE PROTEIN; 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU004475};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121}.
FT DOMAIN 18..184
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EOA24389.1"
SQ SEQUENCE 325 AA; 36515 MW; 522697DF92780424 CRC64;
KNIYDYDLDQ DNAKIVCITD GLTFFGRTIV ERLLLHGYTV RVIVNTPDDL ERVRAMKDET
AKFHGRIEEV SAKLTETESL VDAFDGCYGV FHTSGFIDPS GVSGYSKYMV EIEAKVSENV
MNACTMTQSV RRCLMTSSLL ACLWQNSTQL GRRSVIDHSS WSDESLCKDK KLWYALGKLK
AEKIAWKIAE DKGFKLSTIC AALVTSLNIL HHNPTPTIAY LKGGEEMYGN GVLATVDVNT
LAKVHVKVYE EMNKASFGRY VCFDKVITGE YEAVELANET SISLERIRGD KYDFCEKDLT
KPFCLSNRRL SSLMSTTYPI SCLES
//
