ID R0JDT2_ANAPL Unreviewed; 667 AA.
AC R0JDT2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 22-FEB-2023, entry version 28.
DE SubName: Full=Rho guanine nucleotide exchange factor 17 {ECO:0000313|EMBL:EOA95370.1};
GN ORFNames=Anapl_17747 {ECO:0000313|EMBL:EOA95370.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOA95370.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
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DR EMBL; KB744320; EOA95370.1; -; Genomic_DNA.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR039919; ARHGEF10/ARHGEF17.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR PANTHER; PTHR12877; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR12877:SF15; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 17; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000296049}.
FT DOMAIN 1..162
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 205..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 465..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..257
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..545
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 667 AA; 73294 MW; 543225C31B7FEE0B CRC64;
MKPLKQPENS LLCDPSLVDE IFDQIPELLE HHEQFLEQIH DCVQNWHEKQ KVGDLLVQSF
SKDVLVNIYS AYIDNFLNAK DAVRIAKEAR PAFIKFLEQS MRENKEKQAL SDLMIKPVQR
IPRYELLVKD LLKHTPEDHP DHPFLIDAQR NIKQVAERIN KGMKSAEEVE RNARIVQEIE
SHIEGMEDVR MGGLGVGSWV AVGEGDGGAS SRELGTPSLA KPFCSPAAPK GAAPTPSTKR
QGGASQATNR ESIQKSISRL DEDLNTLGQV SKLSETLSFP HQSLDDVIKD LMAAIHRELA
EKQSLSFSMA FPPNKVELSA AKADGTESFI FEFPNPDARL GFEQAFEDAK KKLASSKNCL
DPEFLKAIPI MKTRSGMQFS CASPSHSSPE NAHEVWVCNS DGYVGQVCLL SIRKEPTVEA
CIAVCSARIL CIASVPGLKX XXXXXAVLRP RHRRHRVPVL ELRLSPRQGT RRTRGQPVLG
AGPGAVXXED AGPQQCLHIS ISGSSLELSE PVDSAHRELV PFDSDDTDDE SSPSPSGTLQ
SQASHSTISS SFGKRVLQNA LQKSCSNCKM LHKTMQGAAQ CHAAMNHTWT AVKCHAEIER
VLQNAMQNQA GSSIILCSNA PPLGICKPYA EIKRVLQNAL QKSCSNCKMP CRNRVGAAQC
HAAMHHT
//
