ID R0LED6_ANAPL Unreviewed; 694 AA.
AC R0LED6;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Myeloperoxidase {ECO:0000313|EMBL:EOB04029.1};
DE Flags: Fragment;
GN ORFNames=Anapl_04897 {ECO:0000313|EMBL:EOB04029.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOB04029.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
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DR EMBL; KB742811; EOB04029.1; -; Genomic_DNA.
DR AlphaFoldDB; R0LED6; -.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd09824; myeloperoxidase_like; 1.
DR Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR InterPro; IPR019791; Haem_peroxidase_animal.
DR InterPro; IPR010255; Haem_peroxidase_sf.
DR InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR PANTHER; PTHR11475:SF63; EOSINOPHIL PEROXIDASE; 1.
DR PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR Pfam; PF03098; An_peroxidase; 1.
DR PRINTS; PR00457; ANPEROXIDASE.
DR SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR PROSITE; PS50292; PEROXIDASE_3; 1.
PE 4: Predicted;
KW Heme {ECO:0000256|PIRSR:PIRSR619791-2};
KW Iron {ECO:0000256|PIRSR:PIRSR619791-2};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxidase {ECO:0000313|EMBL:EOB04029.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000296049}.
FT BINDING 457
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EOB04029.1"
FT NON_TER 694
FT /evidence="ECO:0000313|EMBL:EOB04029.1"
SQ SEQUENCE 694 AA; 79209 MW; F09EB7E4A6E869D6 CRC64;
SIKKNLENDV LTPVELLRYF KQPVAGTRAA VRAADYMETT LTLLKEKLRW AVKGDFNVTD
MLTPAQLGMI FKASGCDQQN EEINCESSGR YRTITGKCNN RRWWLHLGGR SSIWDNNGSL
RPEPDLVALI FFCSSIHWCR KNPLLGASNR ALARWLPADY EDGVSIPHGW TEKKRVSGFP
FPLVRKVSNE IVRFPPAQLK LDQQRSLMFM QWGQFIDHDL DFSPETPARV TFSGKVDCHT
SCAKQPPCFP IKIPPNDPRV KNTRDCLPFI RSAPACDSGK AIREQINALT SFLDGSVVYG
SEVPLANKLR DRTNQLGLLA VNRNFTDRGM AYMPFDYMSK DPCLMVSKGA KIPCFLAGDS
RANEMLELAC MHTLFVREHN RLARGLKRLN PHWNGEKLYQ EARKIVGAMI QIITYRDYLP
LLLGTSLQKW IPCYRGYNEA VDPRISNVFT LAFRFAHASI PPFVGRLNKN YKPINPKLQL
SKTFFGVWRI VKEGGIDPFL RNLMASKAKL MTQKQMVVDE LRDRMFEQVE RIGFDLAALN
MQRGRDHGLP GYISWRQFCR LSKPRGLKSL AQVLKNHSLA KKFMQLYGTP KNIDIWIGAL
AEPFVKGGRV GPLMACLIGT QFRKIRDGDR FWWENKGVFT PRQRSSLAKI SLSRIICDNT
HISKVSRNIF QANSYPHSFV SCNQIPKLDL RAWK
//
