ID R0LJH5_ANAPL Unreviewed; 1236 AA.
AC R0LJH5;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=DNA repair protein REV1 {ECO:0000256|ARBA:ARBA00020399};
DE Flags: Fragment;
GN ORFNames=Anapl_01160 {ECO:0000313|EMBL:EOB05839.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOB05839.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
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DR EMBL; KB742659; EOB05839.1; -; Genomic_DNA.
DR AlphaFoldDB; R0LJH5; -.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR GO; GO:0042276; P:error-prone translesion synthesis; IEA:InterPro.
DR CDD; cd17719; BRCT_Rev1; 1.
DR CDD; cd01701; PolY_Rev1; 1.
DR CDD; cd12145; Rev1_C; 1.
DR CDD; cd19318; Rev1_UBM2; 2.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 6.10.250.1490; -; 1.
DR Gene3D; 6.10.250.1630; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR Gene3D; 1.20.58.1280; DNA repair protein Rev1, C-terminal domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR025527; HUWE1/Rev1_UBM.
DR InterPro; IPR012112; REV1.
DR InterPro; IPR031991; Rev1_C.
DR InterPro; IPR038401; Rev1_C_sf.
DR InterPro; IPR047346; Rev1_UBM1/2.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR45990; DNA REPAIR PROTEIN REV1; 1.
DR PANTHER; PTHR45990:SF1; DNA REPAIR PROTEIN REV1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF00817; IMS; 2.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF21704; POLH-Rev1_HhH; 1.
DR Pfam; PF16727; REV1_C; 1.
DR Pfam; PF14377; UBM; 2.
DR PIRSF; PIRSF036573; REV1; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000296049};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 28..115
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 404..645
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 223..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1026..1136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1032..1048
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1052..1068
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1087..1136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EOB05839.1"
FT NON_TER 1236
FT /evidence="ECO:0000313|EMBL:EOB05839.1"
SQ SEQUENCE 1236 AA; 136134 MW; 0BAEE8E54C036823 CRC64;
GGYMSAKVKK LEDQFRSDSA IEHQRDGNSS SIFSGVAIYV NGFTDPSADE LRRLMMLHGG
QYHVYYSRSK TTHIIATNLP NAKIKELKGE KVVRPEWIME SIKAGRLLSH IPYQLYTKQS
SVQKGLSFNS ICKPEDAMPG PSNIAKDLNR VNHIKKCEME SEITPNGTSS WNEEEEEEDG
GLAFTELEQI LPGRKQNGIQ SQKDSTAIFN GHTHNTCTSA LKTQDCSVPS SNSVASRFSP
GPVQEEDKTE KGMVDFRDCT MQQLQQSNKN TDFSWNTHRT MSNSSSSSSL HSNTKINGAH
HSTVQGPSST KSTSVPNPSK AASLPVSKPS DCNFISDFYS RSRLHHISTW KSELTEFVNS
LQRKNSGVFP GREKLKKWKA GRSALKTDTG NVSVASSAKP QSCIMHVDMD CFFVSVATRN
RPDLKGKPVA VTSNRGAGKA PLRPGANPQL ERQYYQNKLL NGKAEIRVPD KLDSSFWEHP
DSTHMNGGDF NQTVLSMAEI ASCSYEARQV GIKNGMFFGQ AKKLCPNLQA VSYDFDAYKE
VAQTVYEILA SYTHNIEAVS CDEALVDITE ILTETRLTPD EFANAIRTEI KAQTKCTASV
GMGSNILLAR MATRKAKPDG QYHLKPEEVD DFIRGQLVTS LPGVGRTMES KLASLGIRTC
GDLQCASMSK LQKEFGPKTG QMLYRFCRGL DDRPVRTEKE RKSVSAEINY GIRFTQPKEA
EAFLLSLSEE IQRRLEAAGM KGKRLTLKIM VRKAGAPVEP AKYGGHGICD NIARTVTLDH
ATDSAKIIGK ETLNMFHTMK LNISDMRGVG IQVQQLVPIS KTTSAHSAVQ AGHLPGGSHS
VIDLFHVQKA KKCSEEEHKE VFVAAMDLEI SSDSRTCTFL PSRGTHLTSG LNSNVNKTES
AVKCNGLHTP ISVKSRLNLS IEVPSASQLD KSVLEALPPD LREQVEQIYT IQQGETYGES
KKEPINGCST ALLSQPVGTV LLQVPELQEP NANTGINVIA LPAFSQVDPE VFAALPAELQ
AELRDAYDQR QKQPEQQPAN TSVSKNPCLH PKHATMKNKK KIRKKNPVSP AKKIQSPLKN
KLLGSPAKNM PATSGSPQKL IDSFLKQEGT APQQPEAVPS TSDCSGPSAL QTEQPGSFRP
QAPNLAGAVE FNDVKTLLKE WITTISDPME EDILQVVKYC TDLIEEKDLE KLDLVVKYMK
RLMQSSVESV WNMAFDFILD NVQVVLQQTY GSTLKV
//
