ID R1C2G6_EMIHU Unreviewed; 884 AA.
AC R1C2G6;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=GTP diphosphokinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=EMIHUDRAFT_102713 {ECO:0000313|EMBL:EOD16743.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD16743.1};
RN [1] {ECO:0000313|EMBL:EOD16743.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD16743.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD16743}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; KB866687; EOD16743.1; -; Genomic_DNA.
DR RefSeq; XP_005769172.1; XM_005769115.1.
DR STRING; 2903.R1C2G6; -.
DR PaxDb; 2903-EOD16743; -.
DR EnsemblProtists; EOD16743; EOD16743; EMIHUDRAFT_102713.
DR GeneID; 17262891; -.
DR KEGG; ehx:EMIHUDRAFT_102713; -.
DR eggNOG; KOG1157; Eukaryota.
DR HOGENOM; CLU_326091_0_0_1; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR CDD; cd05399; NT_Rel-Spo_like; 1.
DR CDD; cd01668; TGS_RSH; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR007685; RelA_SpoT.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR InterPro; IPR033655; TGS_RelA/SpoT.
DR PANTHER; PTHR43061; GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR43061:SF1; GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF13291; ACT_4; 1.
DR Pfam; PF04607; RelA_SpoT; 1.
DR Pfam; PF02824; TGS; 1.
DR SMART; SM00954; RelA_SpoT; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS51880; TGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000013827}.
FT DOMAIN 539..600
FT /note="TGS"
FT /evidence="ECO:0000259|PROSITE:PS51880"
FT DOMAIN 810..884
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
FT REGION 235..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 289..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 648..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..308
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..453
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 648..672
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 884 AA; 93545 MW; BFA0E430868CE1FA CRC64;
MVCTGAHAAL LFAVAYHPRL SHPGGMLRAR APAVSLTAEQ EEQQRSWQRV QRSASERFLP
RLDVLRSGEA PAPWRLPPAY RAMLAQLLVN AATGDEGALA ARRAWDAFVF ALRYHRRQYR
ASGEPYVASM LAKAEADLPS IMTGLLHDTV EDTGATLELV TERFGPEAEE TMGIFAPLAL
RIGMYTVAAE LETLALAELH PEAAERVAAQ QRAHIASPEL AQVLRELRAA LAQNEGSGGG
SAGGGGAAGE GGAAGGGGAA GEGGALLRAI HVRRASAYRV WRRQQAQLRE REGEGGGAAQ
REAHDEEEED APAGVAETAR VVAAGRRGEG RGALALDLLS LGDWLQRARL LRSFAGPSWN
RPVGDCLRLV LVCATPLGCY EALGLVHQRW RSLGGFKDYI STPKPNHYQS LHTTVLGALS
SPPPPNPATR APAPLPPSLP PPPPLPHPPL PPRTGPGGVL LHLLFRTPEM HQVAEQGIVA
HWRQQARGPA PTLPRCGNRY GWLRSLQDIS DASEAADDSI EAAPGTRPRR AAQMELLADQ
IFCFTPKGDI VPLPRGSSPL DLAYAVHSSI GNRCAGARVN GRLQSIHAVL RNGDRVEVLV
SSQVEPQQSW LALVASGRAR AELRRFFNAK RRAVRAGGGD IRLPALAALP PPPPPPSTVR
ATAPAPPAAP PLPRPKRRRR VVSAGGMAAN GSVASVQSSR TAAAAAAGKD GRAAGDAAGG
PRLQLAKCCR PVPGDPIAGV LRGGGPRPTL CVHREGCRAL QPPPREGSQA GPQAGLQAGL
QAGGEEDERR VAVRWGGQWA KLFGSRYEAR LKLRVDDAPD TLAAIAAEAA RTGATLSSFR
VLSRGRKAGM ARATAHVEVT DLAQLLELMR ALRTLSAVRS VERG
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