ID R1DN99_EMIHU Unreviewed; 1524 AA.
AC R1DN99;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Receptor ligand binding region domain-containing protein {ECO:0000259|Pfam:PF01094};
GN ORFNames=EMIHUDRAFT_454995 {ECO:0000313|EMBL:EOD37048.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD37048.1};
RN [1] {ECO:0000313|EMBL:EOD37048.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD37048.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD37048}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; KB864140; EOD37048.1; -; Genomic_DNA.
DR RefSeq; XP_005789477.1; XM_005789420.1.
DR STRING; 2903.R1DN99; -.
DR PaxDb; 2903-EOD37048; -.
DR EnsemblProtists; EOD37048; EOD37048; EMIHUDRAFT_454995.
DR GeneID; 17282318; -.
DR KEGG; ehx:EMIHUDRAFT_454995; -.
DR eggNOG; KOG1055; Eukaryota.
DR eggNOG; KOG1056; Eukaryota.
DR HOGENOM; CLU_001860_0_0_1; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR Gene3D; 3.40.50.2300; -; 5.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR30483; LEUCINE-SPECIFIC-BINDING PROTEIN; 1.
DR PANTHER; PTHR30483:SF6; PERIPLASMIC BINDING PROTEIN OF ABC TRANSPORTER FOR NATURAL AMINO ACIDS; 1.
DR Pfam; PF01094; ANF_receptor; 2.
DR PRINTS; PR00248; GPCRMGR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 2.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000013827};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..1524
FT /note="Receptor ligand binding region domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014591431"
FT TRANSMEM 989..1013
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 125..486
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
FT DOMAIN 586..913
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
FT REGION 385..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 964..986
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1505..1524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 970..986
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1524 AA; 163710 MW; D371AB7DDE70D1AD CRC64;
MFAVLTLVPA APAATEPCTC ALNWTDPDSG HACREPQFGC PPVACDGPYP PWCVVESLPC
ADPDPDSGIN TGLYGGNWIH CEPEYSPTPP SYPPPPPFAV VRIGALLPRQ LPSGELMHLG
RAEELTSVLM AIEEINNKTD GVADDLLPNT QLLLAHRDSR CDPAFGSDAA YQLLHHAFDG
AGCDALVGAY CSSASIPAAR LAELTATPQV SHSSQSPELS GDDFPFFARV VTSDSLMAVA
LAEATRNLLG VKRVATIACT DAYCTAGVAA FEAAASAQGI TIIESVRFEN GQSNLGEPLG
ALRASCATVF VAIALAEDAD RLLEQALGAR LVGPEFTWVG DIGLFEGLGS LAGRGLPVDD
FRGILAITNS IAPSVAYDGY ASRKRARPST LGDGTNCDPA DDDEGHKLWS VDTDEDRAPR
CFGANNQFPE SVYAPRAYDA VYAVAHAVQA LVDDPLVQRI DGDALMAALL AVRFDGVTGK
VSFSSEPATL GDRAGGVLYD VMNVNASGAW VKLGTWQPAD NWEQSFAGNG QALTRPTPDN
SKPPELVGDT LRVGVFCDDH VGESECQHVM HIIDRINDKK DGFLDDLLPD HTLFYSMVQT
GTTGCAESEA IRRQFDQLYS DLNGVVATIG PFCSDDVAAV TAAEWRAGAD ISTVVLSPSS
TAPILANVGA YPNLLRLSSN DKHVTSAVAA LAERLGWQAI CVLHDDGLWG RGVMQSFTSI
FESSGGKIVN NGTAEFSKAA FDGGNLTGSD LLDQLEDCQI ILLVAYPDAQ RAVFAASYDE
GRLWGPGYAW LNAYPAEEAL YNADGSVNSL KYQALWDEVS SSQGCTNMSP QSRPFCDHDD
DASTLPDYTA MYVDAVIKLA VSADAAIRNG SRPGDADALY ATMLAADTVT GLSGPLVFDD
SGDRLGTLEV LNYRLLTEAS QSGRRLSSVL LPRSLLEFSI VGSYSTATST LQLPDVGALV
FSGGSTEVPQ HSSPPPPPPP PAPPPEPPLS TGVLVVIVLL SVMTPVVVIW VAVREWRRRR
EREHEWTRQQ WLRYLSTGQP VQLEPLTDGN KYHLFLSHSW LSGQDMHKDA VRVMKERLLN
LLPDTKIFLD VDDLASGRGA AEVAMSKILV VFLSDGYLTR PNTVRELLRA MSLQKIVITV
YDERSVYMDK GVLRAAIEAA CLNLSRWGLD GDLAAWGAEV PTTADIFAAL TAQPLLWTRV
PAFMNVTLQA CVTPLVQPKA PMLRPSADGK ANLSPEALQR TVEMLVQPKA LILQSVPSWA
QKGLGRADGK ASLSPEALER AIEMMQAAAE PGAAASTRLY TRAGIGFTWQ RLRAGERFRI
YASPHNPGAL ELTQELSCLL QHLDIELEVT TSVADLTACS HMLLYLDKRT WVSTENDQRI
AALSSDVKAA LAGRVHLLPV HESEPFEYMA GSHAGVKFDD LLDCVDGATP IELLQRQVYA
EVAVPLKEGI YRPASLLLLA RAVGDQTRTS ALRQLTFSSK ELRLPSMTLA EGSASLMSRT
SKYCRSLSSR QSTPHGRRRA LPPL
//
