ID R1DQP2_EMIHU Unreviewed; 481 AA.
AC R1DQP2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=PI3K/PI4K catalytic domain-containing protein {ECO:0000259|Pfam:PF00454};
GN ORFNames=EMIHUDRAFT_464274 {ECO:0000313|EMBL:EOD16830.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD16830.1};
RN [1] {ECO:0000313|EMBL:EOD16830.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD16830.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD16830}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type II PI4K
CC subfamily. {ECO:0000256|ARBA:ARBA00008941}.
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DR EMBL; KB866687; EOD16830.1; -; Genomic_DNA.
DR RefSeq; XP_005769259.1; XM_005769202.1.
DR STRING; 2903.R1DQP2; -.
DR PaxDb; 2903-EOD16830; -.
DR EnsemblProtists; EOD16830; EOD16830; EMIHUDRAFT_464274.
DR GeneID; 17262990; -.
DR KEGG; ehx:EMIHUDRAFT_464274; -.
DR eggNOG; KOG2381; Eukaryota.
DR HOGENOM; CLU_567957_0_0_1; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR InterPro; IPR044571; P4KG1-8.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR PANTHER; PTHR45800; PHOSPHATIDYLINOSITOL 4-KINASE GAMMA; 1.
DR PANTHER; PTHR45800:SF11; PI3K_PI4K CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000013827}.
FT DOMAIN 184..397
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|Pfam:PF00454"
FT REGION 190..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 481 AA; 51976 MW; BA65A83E9B1904E8 CRC64;
MSDTFLTRDT EHPPIPAAAR DCVSTCSSST HCTGTSLAVA RFLTNTRRKS VCFVNPSGSA
LGELSRAAKR MSLTITSSEE QNVGSIVRLI KAIEPPLELP PPSPHVVCGE APPSPHGLCG
EEQNVPRTPA PPARSVSFNT QEVVKAVRRV VSDSSERPSL TEDGTGGVYL IRESSDGVPL
PPVAVFKPAD EEAGSENNPR GLSEHVMREG FRPGGGAVRE RVAYKLDRGF AGVPRTALER
LLLRSKTGKH LTEQCGSIQE FVGDAVGDAS EFRFDGSERS EFDEAQSQRL SVLDSRLFNC
DRHEGNVLVT GARGGGGRRG IVPIDHAFCL PAFGFFREAE FTWRYWASAA VPFGAEVLHH
VASLDVDADV EAARAAGLGE SPCATLRVCT TLLKRLLGGS RAGRATPRDL SEALMREEYD
RPSTLERLCA RALGLLDEGG ELSDAGLVEF VQAEAARRGE EYAPPLEFYA RLEEAMREEY
L
//
