ID R1FFQ8_9PSEU Unreviewed; 363 AA.
AC R1FFQ8;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=GntR family transcriptional regulator fused with aminotransferase {ECO:0000313|EMBL:EOD58443.1};
DE Flags: Fragment;
GN ORFNames=H480_43485 {ECO:0000313|EMBL:EOD58443.1};
OS Amycolatopsis vancoresmycina DSM 44592.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=1292037 {ECO:0000313|EMBL:EOD58443.1, ECO:0000313|Proteomes:UP000014139};
RN [1] {ECO:0000313|EMBL:EOD58443.1, ECO:0000313|Proteomes:UP000014139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44592 {ECO:0000313|EMBL:EOD58443.1,
RC ECO:0000313|Proteomes:UP000014139};
RA Kumar S., Kaur N., Kaur C., Raghava G.P.S., Mayilraj S.;
RT "Draft genome sequence of Amycolatopsis vancoresmycina strain DSM 44592T.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOD58443.1}.
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DR EMBL; AOUO01000761; EOD58443.1; -; Genomic_DNA.
DR AlphaFoldDB; R1FFQ8; -.
DR eggNOG; COG1167; Bacteria.
DR OrthoDB; 5415143at2; -.
DR Proteomes; UP000014139; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:EOD58443.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:EOD58443.1}.
FT DOMAIN 9..75
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT NON_TER 363
FT /evidence="ECO:0000313|EMBL:EOD58443.1"
SQ SEQUENCE 363 AA; 38850 MW; EB57AC580397CD76 CRC64;
MLLAPAGPGP KHEQLARALR RAIRDGVLTG AVPPSRRLAA DLGCSRWVVT QAYAQLVAEG
YLAGHTGSAT RVRPMGGAVA AKEPARAAPP RYDLAPGLPD LRNFPRRPWA EAVREVLATT
PHTDFGLPEP GGHPRLRRIL GDYLRRVRGA APGTVLVCGG VTDGVTSVCR ALVERGHTRL
AVEDPGWTRL RRAAEGAGMT VEPVPVDDEG IDAGRIPAGV RAVLVTPAHQ FPTGSVLSPR
RRAELLGWAR DVDGLILEDD YDAEFRYDRR PVGTVQGTDP GRVALFGSVS KTLSPALGLG
WVLLPPQWTV RAHPPPVVDQ LALAGFVESG GYDRHLRAAR LRYRARRDKL VAALGPARLS
GVA
//
