ID   R1I138_9PSEU            Unreviewed;       474 AA.
AC   R1I138;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Transglycosylase {ECO:0000313|EMBL:EOD69490.1};
GN   ORFNames=H480_05814 {ECO:0000313|EMBL:EOD69490.1};
OS   Amycolatopsis vancoresmycina DSM 44592.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=1292037 {ECO:0000313|EMBL:EOD69490.1, ECO:0000313|Proteomes:UP000014139};
RN   [1] {ECO:0000313|EMBL:EOD69490.1, ECO:0000313|Proteomes:UP000014139}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44592 {ECO:0000313|EMBL:EOD69490.1,
RC   ECO:0000313|Proteomes:UP000014139};
RA   Kumar S., Kaur N., Kaur C., Raghava G.P.S., Mayilraj S.;
RT   "Draft genome sequence of Amycolatopsis vancoresmycina strain DSM 44592T.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transglycosylase family. Rpf subfamily.
CC       {ECO:0000256|ARBA:ARBA00010830}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOD69490.1}.
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DR   EMBL; AOUO01000060; EOD69490.1; -; Genomic_DNA.
DR   RefSeq; WP_003062060.1; NZ_AOUO01000060.1.
DR   AlphaFoldDB; R1I138; -.
DR   PATRIC; fig|1292037.4.peg.1134; -.
DR   eggNOG; COG3583; Bacteria.
DR   OrthoDB; 1404170at2; -.
DR   Proteomes; UP000014139; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd13925; RPF; 1.
DR   Gene3D; 1.10.530.10; -; 1.
DR   Gene3D; 2.20.230.10; Resuscitation-promoting factor rpfb; 1.
DR   InterPro; IPR007137; DUF348.
DR   InterPro; IPR011098; G5_dom.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR010618; RPF.
DR   Pfam; PF03990; DUF348; 2.
DR   Pfam; PF07501; G5; 1.
DR   Pfam; PF06737; Transglycosylas; 1.
DR   SMART; SM01208; G5; 1.
DR   SUPFAM; SSF53955; Lysozyme-like; 1.
DR   PROSITE; PS51109; G5; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        112..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          307..387
FT                   /note="G5"
FT                   /evidence="ECO:0000259|PROSITE:PS51109"
FT   REGION          314..349
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        323..337
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   474 AA;  50677 MW;  1D9A6E0F312350BE CRC64;
     MTGSRQAGAR SAVLERSHFE DTAYGQLDFS DDPNITQQDI LAALGPDADA MMAEIDVDVD
     ELIRLINAET TYLPPIVIPD GLEEDRTASP EARRAALDEG LRQTTKVWKR RFLKGAVLSV
     MISVAGGGAA ALAMNKSITV DVDGHQQTVH SFGGTVGEVL EDAGLSVGEH DSLSPSPQAE
     VGDGGVIKLE RGRQLKMIVD GAEHTSWVRA THLGDALSQL GMAEMDKPGT WMSMPKDGEL
     PLQGATVEIK TLKNITLYDG ANAPKQVKTT AVTTKEFLGE YKLTLGPEDQ AEGGLDVKLT
     DGAEVHISRT GVSTVTQKET IAPPEQRVDD PDLAKGKTSV EDPGTPGEKM VTYKVTQKNG
     KEVGRESISE QVITQPKPKI IHVGTKEAPA PNIGDGSAWD RIAQCESGGN WATNTGNGYY
     GGLQFDKRTW DAYGGDQYAA LPNQASREQQ IAIAEKVRDA RGGYSAWPVC GKKA
//