ID R2PU87_ENTFC Unreviewed; 443 AA.
AC R2PU87;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=CBS domain-containing protein {ECO:0000259|PROSITE:PS51371};
GN ORFNames=UA3_02164 {ECO:0000313|EMBL:EOH54789.1};
OS Enterococcus faecium EnGen0263.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1158553 {ECO:0000313|EMBL:EOH54789.1, ECO:0000313|Proteomes:UP000013667};
RN [1] {ECO:0000313|EMBL:EOH54789.1, ECO:0000313|Proteomes:UP000013667}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAA1280 {ECO:0000313|EMBL:EOH54789.1,
RC ECO:0000313|Proteomes:UP000013667};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Gilmore M.S., Lebreton F., Courvalin P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus faecium UAA1280.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOH54789.1}.
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DR EMBL; AJAD01000015; EOH54789.1; -; Genomic_DNA.
DR RefSeq; WP_002291018.1; NZ_KB946097.1.
DR AlphaFoldDB; R2PU87; -.
DR GeneID; 66498234; -.
DR PATRIC; fig|1158553.3.peg.2178; -.
DR HOGENOM; CLU_054913_0_0_9; -.
DR Proteomes; UP000013667; Unassembled WGS sequence.
DR CDD; cd04596; CBS_pair_DRTGG_assoc; 1.
DR CDD; cd03440; hot_dog; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR Gene3D; 3.40.1390.20; HprK N-terminal domain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR010766; DRTGG.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR028979; Ser_kin/Pase_Hpr-like_N_sf.
DR InterPro; IPR006683; Thioestr_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43080:SF31; CBS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43080; CBS DOMAIN-CONTAINING PROTEIN CBSX3, MITOCHONDRIAL; 1.
DR Pfam; PF03061; 4HBT; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF07085; DRTGG; 1.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF75138; HprK N-terminal domain-like; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703}.
FT DOMAIN 196..254
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 256..318
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 443 AA; 49679 MW; 0F4B13E5764B83E3 CRC64;
MATKHDLILE YIESLPVGNR ISVRSIAKEL NVSEGTAYRA IKDAENVGLV STIQRVGTIR
IERKLKKHIE RLTFGEVVRI IEGDVLGGSA GLDKVLNKFV IGAMTKHAME RYITPGSLMI
VGNRAEVQKL ALEDGAAVLI TGGFNTTAEI AKLADELEMP ILRTSYDTFT VATMINRALS
DQLIKKDIML VSDIYMPAEK THYLHQMDTI SDYQRLSEET QHSRFPVVNR HHRLMGIVTA
KDVLGKSPNQ IIDRVMTKEP ISVKKTMSIA SVSHQMIWDG LEVMPVVSDD LTLEGLITRQ
DVMKAMQLVQ RQPQIADTIS DQISGNIHTI DTDREGNRLE NPKFKFVVTP QMVNGVGTIS
FGVLSEIISD VAQKTMVMNQ KRNILIEQVN LHYLRLIQLE SELDIRPRVL EIGRRSAKLD
IEVFIENTIV SKAIVVCQVM ERS
//
