ID R2RCT3_9ENTE Unreviewed; 411 AA.
AC R2RCT3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=S-methyl-5-thioribose kinase {ECO:0000256|ARBA:ARBA00012128};
DE EC=2.7.1.100 {ECO:0000256|ARBA:ARBA00012128};
GN ORFNames=UAK_04218 {ECO:0000313|EMBL:EOH73809.1};
OS Enterococcus raffinosus ATCC 49464.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1158602 {ECO:0000313|EMBL:EOH73809.1, ECO:0000313|Proteomes:UP000013877};
RN [1] {ECO:0000313|EMBL:EOH73809.1, ECO:0000313|Proteomes:UP000013877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49464 {ECO:0000313|EMBL:EOH73809.1,
RC ECO:0000313|Proteomes:UP000013877};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus raffinosus ATCC_49464.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the methylthioribose kinase family.
CC {ECO:0000256|ARBA:ARBA00010165}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOH73809.1}.
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DR EMBL; AJAL01000022; EOH73809.1; -; Genomic_DNA.
DR RefSeq; WP_010747372.1; NZ_KB946259.1.
DR AlphaFoldDB; R2RCT3; -.
DR PATRIC; fig|1158602.3.peg.4221; -.
DR eggNOG; COG4857; Bacteria.
DR HOGENOM; CLU_033681_0_0_9; -.
DR OrthoDB; 9777791at2; -.
DR Proteomes; UP000013877; Unassembled WGS sequence.
DR GO; GO:0046522; F:S-methyl-5-thioribose kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR009212; Methylthioribose_kinase.
DR NCBIfam; TIGR01767; MTRK; 1.
DR PANTHER; PTHR34273; METHYLTHIORIBOSE KINASE; 1.
DR PANTHER; PTHR34273:SF2; METHYLTHIORIBOSE KINASE; 1.
DR Pfam; PF01636; APH; 1.
DR PIRSF; PIRSF031134; MTRK; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:EOH73809.1};
KW Transferase {ECO:0000313|EMBL:EOH73809.1}.
FT DOMAIN 40..286
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
SQ SEQUENCE 411 AA; 47240 MW; 4700CD90BD7EDFB2 CRC64;
MKVTPRETVA YQEHFLMDTQ KIKQYVVEKL GAFPTEAPLT VTEIGDGNIN YVFRVVNEAT
QESLIIKQAD VLLRSSGRPL AIDRNRIEAE ILRLQNELAP QFVPEVYYYD QKMYALTMED
VSEYQNMRYE LIAKKTFPKF SEEIAEYLAR TLLLTSDLVL DRGEKKQRVK AFINPEMCDI
SEDLVFTEPY DDYKQRNIVT SGNEQFVREN LYENVPLQVE VAILRNNFMN NAQSLLHGDL
HTGSIFINQR GLKVIDPEFA FYGPSGYDIG NVLAHLYFPM VKNLFDETVD QDFHQWSMAT
IEAVYDQVFT KLSVAYDEAV SFSLYRHHAF KDTMLQEIMS DAVGYAGTEI IRRVVGDSKV
KELSLIDFEK KIVAEQMLLK LGIQMVINRQ HITSGRQLVD GIDELAASTI D
//
