ID R3JA41_ENTFL Unreviewed; 426 AA.
AC R3JA41;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Uracil-xanthine permease {ECO:0000313|EMBL:EOJ98229.1};
GN ORFNames=WOK_01826 {ECO:0000313|EMBL:EOJ98229.1};
OS Enterococcus faecalis EnGen0359.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1169307 {ECO:0000313|EMBL:EOJ98229.1, ECO:0000313|Proteomes:UP000013601};
RN [1] {ECO:0000313|EMBL:EOJ98229.1, ECO:0000313|Proteomes:UP000013601}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TR197 {ECO:0000313|EMBL:EOJ98229.1,
RC ECO:0000313|Proteomes:UP000013601};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus faecalis TR197.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOJ98229.1}.
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DR EMBL; ASDV01000011; EOJ98229.1; -; Genomic_DNA.
DR RefSeq; WP_002357410.1; NZ_KB944819.1.
DR AlphaFoldDB; R3JA41; -.
DR GeneID; 60894016; -.
DR PATRIC; fig|1169307.3.peg.1808; -.
DR HOGENOM; CLU_017959_1_2_9; -.
DR Proteomes; UP000013601; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 426 AA; 45444 MW; DA04506A127C9E3E CRC64;
MSEKEFRNED AVLDIKDRPQ AFHWVGLSLQ HLFTMFGATV LVPILVGIDP GIALVSSGLG
TMVYLITTKG KIPAYLGSSF AFIAAMQMLM KSDGYPAIAQ GAMTTGLVYL IVSLIIKKIG
SDWLDKILPP IVVGPVVMVI GLGLAANAAN NAMYNNNVYD FKYIAVALIT LGLTIFYNMF
FKGFLGLIPI LLGIVSGYLV ALAFGIIDLT PIKEAAWFAL PNFEVPFVQY EPKLYLNAIT
TMAPIAFVTM TEHIGHLMVL NKLTKRNFFQ DPGLSKTLMG DGLAQIVAGF VGGPPVTSYG
ENIGVLAITR VHSVFVIGGA AVFAVALGFV GKLSALILSI PGPVISGISF VLFGVIAASG
LKILIDNKIN FDKKKNLLIA SVILVIGIGG LVFKVGTFEL SSMALATVLG IVLNLILPEN
ARSEEQ
//
