ID R3WPM2_9ENTE Unreviewed; 352 AA.
AC R3WPM2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=YegS//BmrU family lipid kinase {ECO:0000313|EMBL:EOL43785.1};
GN ORFNames=UC7_03115 {ECO:0000313|EMBL:EOL43785.1};
OS Enterococcus caccae ATCC BAA-1240.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1158612 {ECO:0000313|EMBL:EOL43785.1, ECO:0000313|Proteomes:UP000013840};
RN [1] {ECO:0000313|EMBL:EOL43785.1, ECO:0000313|Proteomes:UP000013840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1240 {ECO:0000313|EMBL:EOL43785.1,
RC ECO:0000313|Proteomes:UP000013840};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus caccae BAA-1240.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the diacylglycerol/lipid kinase family.
CC {ECO:0000256|ARBA:ARBA00005983}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOL43785.1}.
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DR EMBL; AJAU01000022; EOL43785.1; -; Genomic_DNA.
DR RefSeq; WP_010773191.1; NZ_KE136472.1.
DR AlphaFoldDB; R3WPM2; -.
DR STRING; 317735.RU98_GL000290; -.
DR PATRIC; fig|1158612.3.peg.3085; -.
DR eggNOG; COG1597; Bacteria.
DR OrthoDB; 142078at2; -.
DR Proteomes; UP000013840; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.200.40; -; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR005218; Diacylglycerol/lipid_kinase.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR045540; YegS/DAGK_C.
DR NCBIfam; TIGR00147; YegS/Rv2252/BmrU family lipid kinase; 1.
DR PANTHER; PTHR12358:SF115; DIACYLGLYCEROL KINASE; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF19279; YegS_C; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EOL43785.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..133
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 352 AA; 38753 MW; AEFDA6252E67917F CRC64;
MKKARVIYNP TSGKELVKKN LADILSVVEE CGYETSAFAT TPQENSAKNE ARRVAELGFD
LIVAAGGDGT INEVVNGIAP LEKRPSMAII PAGTTNDYAR ALKIPRDNIL KAAEVIKKNQ
TVKMDIGKAK DSYFINIAAG GHLTELTYEV PSELKSIFGY LAYLAKGAEM LPRVKPIKMR
MEYDEGVYEG NASMFFLGLT NSVGGFEKIA PDAKLDDGKF SLIIVKTANV FEILHLAALM
LNGGKHIEDS RLIYTKTSHL YAETLESNSR MMINLDGEYG GDAPMEFTNL HQHIEMFANA
DAIPSNAIMG SVLDDYNEEA DEEDEYLETS KEFVKEVERL TEEDIDNNGK IG
//
