ID R4FD36_9BACI Unreviewed; 97 AA.
AC R4FD36;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Cell division protein ZapA {ECO:0000256|ARBA:ARBA00015195, ECO:0000256|HAMAP-Rule:MF_02013};
DE AltName: Full=Z ring-associated protein ZapA {ECO:0000256|ARBA:ARBA00033158, ECO:0000256|HAMAP-Rule:MF_02013};
GN Name=zapA {ECO:0000256|HAMAP-Rule:MF_02013};
GN ORFNames=KN10_1161 {ECO:0000313|EMBL:GAC90725.1};
OS Anoxybacillus flavithermus NBRC 109594.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Anoxybacillus.
OX NCBI_TaxID=1315967 {ECO:0000313|EMBL:GAC90725.1, ECO:0000313|Proteomes:UP000013057};
RN [1] {ECO:0000313|Proteomes:UP000013057}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 109594 {ECO:0000313|Proteomes:UP000013057};
RA Matsutani M., Shirakihara Y., Imada K., Yakushi T., Matsushita K.;
RT "Draft Genome Sequence of a Thermophilic Member of the Bacillaceae,
RT Anoxybacillus flavithermus Strain Kn10, Isolated from the Kan-nawa Hot
RT Spring in Japan.";
RL Genome Announc.1:e00311-13(2013).
CC -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC GTPase activity, therefore promoting FtsZ assembly into bundles of
CC protofilaments necessary for the formation of the division Z ring. It
CC is recruited early at mid-cell but it is not essential for cell
CC division. {ECO:0000256|ARBA:ARBA00024910, ECO:0000256|HAMAP-
CC Rule:MF_02013}.
CC -!- SUBUNIT: Homodimer. Interacts with FtsZ.
CC {ECO:0000256|ARBA:ARBA00026068, ECO:0000256|HAMAP-Rule:MF_02013}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_02013}.
CC Note=Localizes at mid-cell. In sporulating cells, localizes near the
CC cell poles. {ECO:0000256|HAMAP-Rule:MF_02013}.
CC -!- SIMILARITY: Belongs to the ZapA family. Type 2 subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_02013}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAC90725.1}.
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DR EMBL; BARH01000009; GAC90725.1; -; Genomic_DNA.
DR AlphaFoldDB; R4FD36; -.
DR Proteomes; UP000013057; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR Gene3D; 6.10.250.790; -; 1.
DR HAMAP; MF_02013; ZapA_type2; 1.
DR InterPro; IPR007838; Cell_div_ZapA-like.
DR InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR InterPro; IPR023688; Cell_div_ZapA_firmicutes.
DR PANTHER; PTHR34981; CELL DIVISION PROTEIN ZAPA; 1.
DR PANTHER; PTHR34981:SF1; CELL DIVISION PROTEIN ZAPA; 1.
DR Pfam; PF05164; ZapA; 1.
DR SUPFAM; SSF102829; Cell division protein ZapA-like; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP-
KW Rule:MF_02013};
KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP-
KW Rule:MF_02013}; Coiled coil {ECO:0000256|HAMAP-Rule:MF_02013};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_02013};
KW Septation {ECO:0000256|ARBA:ARBA00023210, ECO:0000256|HAMAP-Rule:MF_02013}.
SQ SEQUENCE 97 AA; 10956 MW; 1332226D0B6B87EE CRC64;
MNGGNNLAEQ KKTRITVDIY GQQYSIVGTE SSSHIRLVAS IVDDKMREIS AKNPTLDTSK
LAVLTAVNIV HEYIELKDEY ERLLRKMNKE KDDDSGD
//
