ID R4I066_MELGA Unreviewed; 68 AA.
AC R4I066;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Insulin-like growth factor-1 {ECO:0000313|EMBL:AEW10514.1};
DE Flags: Fragment;
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|EMBL:AEW10514.1};
RN [1] {ECO:0000313|EMBL:AEW10514.1}
RP NUCLEOTIDE SEQUENCE.
RA Bhanja S.K., Goel A., Mehra M.;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU000406}.
CC -!- SIMILARITY: Belongs to the insulin family.
CC {ECO:0000256|ARBA:ARBA00009034, ECO:0000256|RuleBase:RU000406}.
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DR EMBL; JN942587; AEW10514.1; -; mRNA.
DR AlphaFoldDB; R4I066; -.
DR HOGENOM; CLU_123939_0_0_1; -.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0010648; P:negative regulation of cell communication; IEA:UniProt.
DR GO; GO:0023057; P:negative regulation of signaling; IEA:UniProt.
DR CDD; cd04368; IlGF; 1.
DR Gene3D; 1.10.100.10; Insulin-like; 1.
DR InterPro; IPR022341; IGF-I.
DR InterPro; IPR016179; Insulin-like.
DR InterPro; IPR022350; Insulin-like_growth_factor.
DR InterPro; IPR036438; Insulin-like_sf.
DR InterPro; IPR022353; Insulin_CS.
DR PANTHER; PTHR46845; INSULIN-LIKE GROWTH FACTOR I; 1.
DR PANTHER; PTHR46845:SF1; INSULIN-LIKE GROWTH FACTOR I; 1.
DR Pfam; PF00049; Insulin; 1.
DR PRINTS; PR02002; INSLNLIKEGF.
DR PRINTS; PR02005; INSLNLIKEGF1.
DR SMART; SM00078; IlGF; 1.
DR SUPFAM; SSF56994; Insulin-like; 1.
DR PROSITE; PS00262; INSULIN; 1.
PE 2: Evidence at transcript level;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030};
KW Secreted {ECO:0000256|RuleBase:RU000406}.
FT DOMAIN 1..55
FT /note="Insulin-like"
FT /evidence="ECO:0000259|SMART:SM00078"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEW10514.1"
FT NON_TER 68
FT /evidence="ECO:0000313|EMBL:AEW10514.1"
SQ SEQUENCE 68 AA; 7642 MW; F7E4F1085200EFDF CRC64;
GAELVDALQF VCGDRGFYFS KPTGYGSSSR RLHHKGIVDE CCFQSCDLRR LEMYCAPIKP
PKSARSVR
//
