ID   R4JA55_9REOV            Unreviewed;       329 AA.
AC   R4JA55;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=VP6 {ECO:0000313|EMBL:AGJ83589.1, ECO:0000313|EMBL:QPK39781.1};
OS   Bluetongue virus 18.
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Sedoreoviridae; Orbivirus; Bluetongue virus.
OX   NCBI_TaxID=197781 {ECO:0000313|EMBL:AGJ83589.1, ECO:0000313|Proteomes:UP000101040};
RN   [1] {ECO:0000313|EMBL:AGJ83589.1, ECO:0000313|Proteomes:UP000101040}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BT32/76 {ECO:0000313|EMBL:AGJ83589.1};
RA   Koekemoer O., DeCastro M., Michuki G.;
RT   "Genome sequences of bluetongue virus prototype strains.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:QPK39781.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=18/Labstr/ZAF/2020/Howell_DVTD_ref 18
RC   {ECO:0000313|EMBL:QPK39781.1};
RA   Coetzee P., Guthrie A.J., Martin D., Venter E.H., Von Teichman B.,
RA   Ebersohn K., Maclachlan J.N., Le Grange M., van Schalkwyk A.;
RT   "Whole genome sequence characterization of bluetongue virus field and
RT   vaccine strains from southern Africa.";
RL   Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Surrounds and interacts with the genomic dsRNA. Possesses
CC       ss- and dsRNA-binding capacity. Its hydrophilic nature and capability
CC       to bind ss- and dsRNA suggest that it interacts with BTV genomic RNA.
CC       {ECO:0000256|ARBA:ARBA00037248}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000256|ARBA:ARBA00004328}.
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DR   EMBL; JX272447; AGJ83589.1; -; Genomic_RNA.
DR   EMBL; MT078377; QPK39781.1; -; Genomic_RNA.
DR   Proteomes; UP000101040; Genome.
DR   GO; GO:0019028; C:viral capsid; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   InterPro; IPR001399; Orbi_VP6.
DR   Pfam; PF01516; Orbi_VP6; 1.
DR   PRINTS; PR00902; VP6CAPSID.
PE   4: Predicted;
FT   REGION          27..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          180..236
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..83
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        180..231
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   329 AA;  35661 MW;  C69D493814953F5B CRC64;
     MSAAMLLAPG DVIKRSSEEL KQRQIQINLI DWTEGESEKE SKAEAKEGDK AEELKDGEGT
     QSESSQKKES SKETKDADVD RRIHTAVGSG SSAKGPGERA NENVDRGDGK VGGGGGDADA
     GVGTTGANGR RWVVLTEEIA RAIESKYGTK IDVYRDEVPA QIIEVERSLQ KELGISREGV
     AEQTERLRDL RRKEKSGAHA KAAERGRRKQ GKKPHGDAQR EGTEEEKTSE EPASVGITIE
     GVMSQKKLLS MIGGVERKMA PIGARESAVM LVSNSIKDVV RATAYFTAPT GDPHWKEVAR
     EASKKKNILA YTSTGGDVKT EFLHLIDHL
//