ID R4M683_MYCTX Unreviewed; 605 AA.
AC R4M683;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=4-alpha-glucanotransferase {ECO:0000256|ARBA:ARBA00020295, ECO:0000256|RuleBase:RU361207};
DE EC=2.4.1.25 {ECO:0000256|ARBA:ARBA00012560, ECO:0000256|RuleBase:RU361207};
DE AltName: Full=Amylomaltase {ECO:0000256|ARBA:ARBA00031423, ECO:0000256|RuleBase:RU361207};
DE AltName: Full=Disproportionating enzyme {ECO:0000256|ARBA:ARBA00031501, ECO:0000256|RuleBase:RU361207};
GN ORFNames=I917_12655 {ECO:0000313|EMBL:AGL23426.1};
OS Mycobacterium tuberculosis str. Haarlem/NITR202.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=1304279 {ECO:0000313|EMBL:AGL23426.1, ECO:0000313|Proteomes:UP000013563};
RN [1] {ECO:0000313|EMBL:AGL23426.1, ECO:0000313|Proteomes:UP000013563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Haarlem/NITR202 {ECO:0000313|EMBL:AGL23426.1,
RC ECO:0000313|Proteomes:UP000013563};
RX PubMed=23788533;
RA Narayanan S., Deshpande U.;
RT "Whole-Genome Sequences of Four Clinical Isolates of Mycobacterium
RT tuberculosis from Tamil Nadu, South India.";
RL Genome Announc. 1:e00186-13(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Transfers a segment of a (1->4)-alpha-D-glucan to a new
CC position in an acceptor, which may be glucose or a (1->4)-alpha-D-
CC glucan.; EC=2.4.1.25; Evidence={ECO:0000256|ARBA:ARBA00000439,
CC ECO:0000256|RuleBase:RU361207};
CC -!- SIMILARITY: Belongs to the disproportionating enzyme family.
CC {ECO:0000256|ARBA:ARBA00005684, ECO:0000256|RuleBase:RU361207}.
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DR EMBL; CP004886; AGL23426.1; -; Genomic_DNA.
DR KEGG; mtuh:I917_12655; -.
DR PATRIC; fig|1304279.3.peg.1697; -.
DR HOGENOM; CLU_022072_1_0_11; -.
DR BioCyc; MTUB1304279:G13AB-1678-MONOMER; -.
DR Proteomes; UP000013563; Chromosome.
DR GO; GO:0004134; F:4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0102500; F:beta-maltose 4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR003385; Glyco_hydro_77.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR NCBIfam; TIGR00217; malQ; 1.
DR PANTHER; PTHR32438; 4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC/AMYLOPLASTIC; 1.
DR PANTHER; PTHR32438:SF5; 4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC_AMYLOPLASTIC; 1.
DR Pfam; PF02446; Glyco_hydro_77; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU361207};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU361207};
KW Transferase {ECO:0000256|RuleBase:RU361207, ECO:0000313|EMBL:AGL23426.1}.
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 548..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 605 AA; 66570 MW; 769C192084A4D7B7 CRC64;
MTDAGSGEXX XXXPXXXPLG YHRVNLRSGD SQASAAVVVT PDWLGLPDKL AGRRAWGLAV
QLYSVRSRQS WGIGDLTDLA NLALWSASAH GAGYVLVNPL HAATLPGPAG RSKPIEPSPY
LPTSRRFVNP LYLRVEAIPE LVDLPKRGRV QRLRTNVQQH ADQLDTIDRD SAWAAKRAAL
KLVHRVPRSA GRELAYAAFR TREGRALDDF ATWCALAETY GDDWHRWPKS LRHPDASGVA
DFVDKHADAV DFHRWLQWQL DEQLASAQSQ ALRAGMSLGI MADLAVGVHP NGADAWALQD
VLAQGVTAGA PPDEFNQLGQ DWSQPPWRPD RLAEQEYRPF RALIQAALRH AGAVRIDHII
GLFRLWWIPD GAPPTQGTYV RYDHDAMIGI VALEAHRAGA VVVGEDLGTV EPWVRDYLLL
RGLLGTSILW FEQDRDCGPA GTPLPAERWR EYCLSSVTTH DLPPTAGYLA GDQVRLRESL
GLLTNPVEAE LESARADRAA WMAELRRVGL LADGAEPDSE EAVLALYRYL GRTPSRLLAV
ALTDAVGDRR TQNQPGTTDE YPNWRVPLTG PDGQPXXLED IFTDRRAATL AEAVRAATTS
PMSCW
//
