ID R4UCK5_9MOLU Unreviewed; 228 AA.
AC R4UCK5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase {ECO:0000313|EMBL:AGM25619.1};
GN Name=ispD {ECO:0000313|EMBL:AGM25619.1};
GN ORFNames=SSYRP_v1c00230 {ECO:0000313|EMBL:AGM25619.1};
OS Spiroplasma syrphidicola EA-1.
OC Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales; Spiroplasmataceae;
OC Spiroplasma.
OX NCBI_TaxID=1276229 {ECO:0000313|EMBL:AGM25619.1, ECO:0000313|Proteomes:UP000013963};
RN [1] {ECO:0000313|EMBL:AGM25619.1, ECO:0000313|Proteomes:UP000013963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EA-1 {ECO:0000313|EMBL:AGM25619.1};
RX PubMed=23711669; DOI=10.1093/gbe/evt084;
RA Ku C., Lo W.S., Chen L.L., Kuo C.H.;
RT "Complete genomes of two dipteran-associated spiroplasmas provided insights
RT into the origin, dynamics, and impacts of viral invasion in spiroplasma.";
RL Genome Biol. Evol. 5:1151-1164(2013).
CC -!- FUNCTION: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-
CC erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
CC {ECO:0000256|ARBA:ARBA00002459}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP005078; AGM25619.1; -; Genomic_DNA.
DR RefSeq; WP_016340281.1; NC_021284.1.
DR AlphaFoldDB; R4UCK5; -.
DR STRING; 1276229.SSYRP_v1c00230; -.
DR KEGG; ssyr:SSYRP_v1c00230; -.
DR PATRIC; fig|1276229.3.peg.23; -.
DR eggNOG; COG1211; Bacteria.
DR HOGENOM; CLU_061281_1_0_14; -.
DR OrthoDB; 9806837at2; -.
DR Proteomes; UP000013963; Chromosome.
DR GO; GO:0070567; F:cytidylyltransferase activity; IEA:InterPro.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR InterPro; IPR034683; IspD/TarI.
DR InterPro; IPR018294; ISPD_synthase_CS.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR32125; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR32125:SF4; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR Pfam; PF01128; IspD; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR PROSITE; PS01295; ISPD; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:AGM25619.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000013963};
KW Transferase {ECO:0000313|EMBL:AGM25619.1}.
SQ SEQUENCE 228 AA; 26382 MW; 90F9C14F8064C508 CRC64;
MENYTVIIPA AGTSQRFKHQ DHKLLYRGQQ TERVIEKTIR IFLEDPFCHA IIIGVNDLVG
QFLQEHYANE KKITLVKGKD NRADTVLVCL QATEIKTTLT LVHDGARCFL TPTLRDQMVT
FFEQNNCQVL IPVLPITDTI RMMKNNKVVK TMIREELVTV QTPQLFKTAI LQKAYQCYHQ
QKTTLPSVIY DDAYLIELFC PEVEITTIVG EQSNQKITYY EDVKFGKY
//
