ID R4W058_9EURY Unreviewed; 524 AA.
AC R4W058;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=ORC1-type DNA replication protein {ECO:0000256|HAMAP-Rule:MF_01407};
GN ORFNames=L593_09605 {ECO:0000313|EMBL:AGN01866.1};
OS Salinarchaeum sp. Harcht-Bsk1.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Natronoarchaeaceae; Salinarchaeum.
OX NCBI_TaxID=1333523 {ECO:0000313|EMBL:AGN01866.1, ECO:0000313|Proteomes:UP000014072};
RN [1] {ECO:0000313|EMBL:AGN01866.1, ECO:0000313|Proteomes:UP000014072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Harcht-Bsk1 {ECO:0000313|EMBL:AGN01866.1};
RX PubMed=23868130;
RA Dominova I.N., Sorokin D.Y., Kublanov I.V., Patrushev M.V.,
RA Toshchakov S.V.;
RT "Complete Genome Sequence of Salinarchaeum sp. Strain HArcht-Bsk1T,
RT Isolated from Hypersaline Lake Baskunchak, Russia.";
RL Genome Announc. 1:E00505-13(2013).
CC -!- FUNCTION: Involved in regulation of DNA replication.
CC {ECO:0000256|HAMAP-Rule:MF_01407}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000256|HAMAP-
CC Rule:MF_01407}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP005962; AGN01866.1; -; Genomic_DNA.
DR AlphaFoldDB; R4W058; -.
DR STRING; 1333523.L593_09605; -.
DR KEGG; sali:L593_09605; -.
DR PATRIC; fig|1333523.5.peg.1977; -.
DR eggNOG; arCOG00467; Archaea.
DR HOGENOM; CLU_025112_3_1_2; -.
DR Proteomes; UP000014072; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd00009; AAA; 1.
DR CDD; cd08768; Cdc6_C; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR015163; Cdc6_C.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR PANTHER; PTHR10763:SF22; ORC1-TYPE DNA REPLICATION PROTEIN 3; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF09079; Cdc6_C; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01074; Cdc6_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_01407}; Cell cycle {ECO:0000313|EMBL:AGN01866.1};
KW Cell division {ECO:0000313|EMBL:AGN01866.1};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705, ECO:0000256|HAMAP-
KW Rule:MF_01407};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_01407}; Reference proteome {ECO:0000313|Proteomes:UP000014072}.
FT DOMAIN 130..338
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 432..514
FT /note="Cdc6 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01074"
FT REGION 1..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 188..215
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 142..146
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 337
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 349
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
SQ SEQUENCE 524 AA; 57430 MW; AE85A3AD84C6FEA7 CRC64;
MNENDASAMD ESEDAEHADG SGSEGEADDP LGGAGDGDGR AGSDAVGDGS DADREESGLA
AATADLPADG AAPGLDDEGG GLFDELLAGE RIFEDKEVLR PSYTPNRLPH RGSQINEIAT
VLVSALRGDT PSNILVYGKT GTGKTASAKY VSQELERSAS EYDVDCEVEY INCEVTDTQY
RVLAQLGNEF IEDNLERAED DISELTAIVD AVNVERANEL GFEDLAAVRD RIEELRAYTE
TAEEIPMTGW PTDRVYQAFF EAIDLYERVL VFMFDEIDKL VEKSGDDTLY NLSRINSGLD
RSKVSIIGIS NDLKFTDFLD PRVKSSLGEE EIVFPPYDAE QISDILDQRA EIAYRQDALE
QDVIPLCSAF AAQEHGDARR ALDLLRCAGE FAERDGEDCV GAEHVRRAQD KIELDRIVEA
VRTLPTQSKL VLLSIIELDE DGESRVTTGE VYNVYRTLAE EAGLDPLTQR RATDLISELD
MLGIVNAVVV SKGRYGRTKE ISVSVPTDRT REVIEQDARL GEDE
//
