ID   R4YK34_OLEAN            Unreviewed;       840 AA.
AC   R4YK34;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   SubName: Full=Type I restriction enzyme EcoAI R protein {ECO:0000313|EMBL:CCK74836.1};
DE            EC=3.1.21.3 {ECO:0000313|EMBL:CCK74836.1};
GN   Name=hsdR {ECO:0000313|EMBL:CCK74836.1};
GN   ORFNames=OLEAN_C06600 {ECO:0000313|EMBL:CCK74836.1};
OS   Oleispira antarctica RB-8.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Oceanospirillaceae; Oleispira.
OX   NCBI_TaxID=698738 {ECO:0000313|EMBL:CCK74836.1, ECO:0000313|Proteomes:UP000032749};
RN   [1] {ECO:0000313|EMBL:CCK74836.1, ECO:0000313|Proteomes:UP000032749}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23877221; DOI=10.1038/ncomms3156;
RA   Kube M., Chernikova T.N., Al-Ramahi Y., Beloqui A., Lopez-Cortez N.,
RA   Guazzaroni M.E., Heipieper H.J., Klages S., Kotsyurbenko O.R., Langer I.,
RA   Nechitaylo T.Y., Lunsdorf H., Fernandez M., Juarez S., Ciordia S.,
RA   Singer A., Kagan O., Egorova O., Petit P.A., Stogios P., Kim Y.,
RA   Tchigvintsev A., Flick R., Denaro R., Genovese M., Albar J.P., Reva O.N.,
RA   Martinez-Gomariz M., Tran H., Ferrer M., Savchenko A., Yakunin A.F.,
RA   Yakimov M.M., Golyshina O.V., Reinhardt R., Golyshin P.N.;
RT   "Genome sequence and functional genomic analysis of the oil-degrading
RT   bacterium Oleispira antarctica.";
RL   Nat. Commun. 4:2156-2156(2013).
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DR   EMBL; FO203512; CCK74836.1; -; Genomic_DNA.
DR   AlphaFoldDB; R4YK34; -.
DR   STRING; 698738.OLEAN_C06600; -.
DR   REBASE; 65313; OanRB8ORF6580P.
DR   KEGG; oai:OLEAN_C06600; -.
DR   PATRIC; fig|698738.3.peg.678; -.
DR   HOGENOM; CLU_018958_0_0_6; -.
DR   OrthoDB; 9804086at2; -.
DR   Proteomes; UP000032749; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0009035; F:type I site-specific deoxyribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0006304; P:DNA modification; IEA:InterPro.
DR   CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR   CDD; cd18799; SF2_C_EcoAI-like; 1.
DR   Gene3D; 3.90.1570.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013670; EcoEI_R_C_dom.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR029464; HSDR_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR   PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR   Pfam; PF08463; EcoEI_R_C; 1.
DR   Pfam; PF13588; HSDR_N_2; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:CCK74836.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032749}.
FT   DOMAIN          185..345
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   REGION          583..643
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        593..607
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   840 AA;  95171 MW;  D1B7EC2AA8A82D40 CRC64;
     MVRTMDKKAL SEADIISKYI MPAVKNSGWD DMLQIRQEVA LRDGKVIVRG NVGMRKTVKS
     ADIVLYHKPN MPLAVIEAKA NKHEIGKGMQ QGLDYARLLD VPFVFASNGD GFIFHDKTAP
     ANGGQLETEI SLDEFPSPQE LWAKYCAFKG YTEHQLPFIT QDYFDDGSGK APRYYQLQAI
     NKTVEAVSRG QNRNLLVMAT GTGKTYTAFQ IIWRLWKAKQ KKRILFLADR NILVDQTKSN
     DFQPFGTAMT KVTGRTVDPA YEIHLALYQA LTGPEESQKA YKQVDPDFFD LIVIDECHRG
     SASEESAWRE ILEYFSSATQ IGLTATPKET EEVSNIDYFG EPVYTYSLKE GIEDGFLAPY
     KVIRVDLDVD VQGWRPTKGM VDKNGEIITD RIYNQKDFDR VMVIDERTQV VAETITAYLK
     RTDPMAKTIV FCNDIDHAER MRRALVNLNP EQVAKNEKYV MKITGDDELG KAQLDSFINP
     RKAYPVIATT SELMTTGVDA KTCKLIVLDQ NIQSMTKFKQ IIGRGTRIDD RYGKLWFTIL
     DFKKATELFA DERFDGIPEK VMVTTTEDIT DLESDKFDDE FAATNSETSE TDSETDSENR
     EGISEGEEGY ADDGTGNTFE TGQGSNEGEW KDGPIEGDGG EKEPYIKFHV SGVTVKKLAE
     RVQYYDSDGK LVTESFKDYT RKTVMKEFGT LDDFIKKWNS TERKQAIIDE LADAGVIWAA
     LEEDISRDLD PFDLICHVAF DQPPLTRKER ANNVKKRNYF GKYSETAQQV LTNLLEKYEN
     SGVSEIESKQ VLKVTPFTQY GRPLEIKKSA FGGKEQYEQA ISELEDALYD NSLNDEPKRA
//