ID R5EQ64_9GAMM Unreviewed; 345 AA.
AC R5EQ64;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=UDP-N-acetylglucosamine 4 6-dehydratase {ECO:0000313|EMBL:CCX90777.1};
GN ORFNames=BN779_01954 {ECO:0000313|EMBL:CCX90777.1};
OS Succinatimonas sp. CAG:777.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Succinivibrionaceae; Succinatimonas.
OX NCBI_TaxID=1262974 {ECO:0000313|EMBL:CCX90777.1, ECO:0000313|Proteomes:UP000018241};
RN [1] {ECO:0000313|EMBL:CCX90777.1, ECO:0000313|Proteomes:UP000018241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:777 {ECO:0000313|Proteomes:UP000018241};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-alpha-D-glucose = UDP-alpha-D-galactose;
CC Xref=Rhea:RHEA:22168, ChEBI:CHEBI:58885, ChEBI:CHEBI:66914;
CC EC=5.1.3.2; Evidence={ECO:0000256|ARBA:ARBA00000083};
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCX90777.1}.
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DR EMBL; CAXH010000019; CCX90777.1; -; Genomic_DNA.
DR AlphaFoldDB; R5EQ64; -.
DR STRING; 1262974.BN779_01954; -.
DR Proteomes; UP000018241; Unassembled WGS sequence.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR InterPro; IPR020025; PseB.
DR NCBIfam; TIGR03589; PseB; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43318:SF2; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE (INVERTING); 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018241}.
FT DOMAIN 16..291
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 345 AA; 38703 MW; F7C0B1B789CCC58B CRC64;
MDIKQSISEL LKDKTILVTG GTGSFGNKFI KTVLDEYPVK KVIVYSRDEL KQYEMQQRLA
KYSSKMRYFI GDVRDLTRLN LAMKGVDIVV HAAAIKQVPA AEYNPMECIK TNINGAENVI
EAAMANDIEK VVALSTDKAA NPINLYGATK LCSDKLFTAA NNLVGLGRTR FAVVRYGNVS
GSRGSVVPFF KKLLAEKAEF IPITDMKMTR FWISLEQGVN FVLKTLVRMH GGEVFVPKIP
SINIVDLATA IAPNLPQKEV GIRPGEKIHE LMCPKDDSMH VIEFNDFFII RPSITFNSRS
SDCYKTTMLG EQGKPVELGF EYNSKNNPNF LNVEEIRDFL QKQEK
//
