ID   R5ILA3_9CLOT            Unreviewed;       279 AA.
AC   R5ILA3;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=DUF218 domain-containing protein {ECO:0000259|Pfam:PF02698};
GN   ORFNames=BN757_02444 {ECO:0000313|EMBL:CCY42918.1};
OS   Clostridium sp. CAG:7.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262832 {ECO:0000313|EMBL:CCY42918.1, ECO:0000313|Proteomes:UP000018268};
RN   [1] {ECO:0000313|EMBL:CCY42918.1, ECO:0000313|Proteomes:UP000018268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:7 {ECO:0000313|Proteomes:UP000018268};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCY42918.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAYE010000116; CCY42918.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5ILA3; -.
DR   STRING; 1262832.BN757_02444; -.
DR   Proteomes; UP000018268; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd06259; YdcF-like; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR003848; DUF218.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR30336; INNER MEMBRANE PROTEIN, PROBABLE PERMEASE; 1.
DR   PANTHER; PTHR30336:SF6; INTEGRAL MEMBRANE PROTEIN-RELATED; 1.
DR   Pfam; PF02698; DUF218; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018268};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        31..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        61..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          97..248
FT                   /note="DUF218"
FT                   /evidence="ECO:0000259|Pfam:PF02698"
SQ   SEQUENCE   279 AA;  31522 MW;  067BC0E44DA6E27E CRC64;
     MADMILLGLA IICTAYFMVI VFYAGMGTSF AFIWLFFAAL CVFLVYGKWY YRKNMDRIPQ
     WVPVSIVTTC IAGVVIMAAL CIMVFMGAAA SEERNLDYVI VLGARVKEHT VSNSLKKRLD
     KAIEYAEKNP ETYLVLSGGK GPDEPVSEAQ AMYQYLVYNG VRPSQLLLEE HSVSTVENLA
     YSKIIIDSHR EVIRHQREER NRLTFQREPK GGYLIAADKP LDVGVLTSNF HVYRACMIAK
     KWGFENVYGI SAQSDPVLFI HLCVRECASI VKDRIMGNM
//