ID   R5IXK0_9CLOT            Unreviewed;       513 AA.
AC   R5IXK0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=Putative membrane protein {ECO:0000313|EMBL:CCY41446.1};
GN   ORFNames=BN757_01689 {ECO:0000313|EMBL:CCY41446.1};
OS   Clostridium sp. CAG:7.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262832 {ECO:0000313|EMBL:CCY41446.1, ECO:0000313|Proteomes:UP000018268};
RN   [1] {ECO:0000313|EMBL:CCY41446.1, ECO:0000313|Proteomes:UP000018268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:7 {ECO:0000313|Proteomes:UP000018268};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCY41446.1}.
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DR   EMBL; CAYE010000058; CCY41446.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5IXK0; -.
DR   STRING; 1262832.BN757_01689; -.
DR   Proteomes; UP000018268; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd00371; HMA; 1.
DR   Gene3D; 3.30.70.100; -; 1.
DR   Gene3D; 2.60.40.420; Cupredoxins - blue copper proteins; 1.
DR   InterPro; IPR008972; Cupredoxin.
DR   InterPro; IPR017969; Heavy-metal-associated_CS.
DR   InterPro; IPR006121; HMA_dom.
DR   InterPro; IPR036163; HMA_dom_sf.
DR   InterPro; IPR039447; UreH-like_TM_dom.
DR   PANTHER; PTHR42208; HEAVY METAL TRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR42208:SF1; HEAVY METAL TRANSPORTER-RELATED; 1.
DR   Pfam; PF13386; DsbD_2; 1.
DR   Pfam; PF00403; HMA; 1.
DR   SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR   PROSITE; PS01047; HMA_1; 1.
DR   PROSITE; PS50846; HMA_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018268};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        84..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        118..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        208..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        256..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        323..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          4..70
FT                   /note="HMA"
FT                   /evidence="ECO:0000259|PROSITE:PS50846"
FT   REGION          344..386
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          477..513
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   513 AA;  55209 MW;  6335EF6200BEFD14 CRC64;
     MKILRKTLHI GGMSCVNCEH RIRYVLKTAP GIQDATVSYN TGLAHVTYDT DTISLKQIRE
     IIEKNGYTTL PETGTSDYDM KKNFVSLAVI LFLYALLQHF GILNLLAPGQ LADTKMGYGM
     LFVIGLITSV HCIAMCGGIN LSQCIPQPSN ASDVSGSSRA LDIFLPALLY NTGRVISYTA
     IGFLLGLVGM LLGAGTQTEI SYFLQGSLKM IAGIFMVIMG INMLGIFPWL RPLTLRIPRF
     LSTKVLKKRA SSRQPLFVGL LNGLMPCGPL QSMQIVALAC QNPFSGALSM FLFSLGTVPL
     MLGLGSLVSV LGKRFAKKMT TVGAILVVVL GLAMFSQGTA LAGISEGPEN SQNTANPQNT
     GTSEDQGTST DTTDSSNAAD KTPQDENANN IQVIYSTLQR GRYPDIKVQT GVPIKWIINA
     PKGSLNGCNY RMLLRSFGIE HTLSEGENVI EFTPSKSGTF QYTCWMGMIR GNITVTDTLE
     TSPTDPDTST GAEETDPETE PFFNGSGMGC CGS
//