ID R5PVS9_9FIRM Unreviewed; 900 AA.
AC R5PVS9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=FtsK/SpoIIIE family protein {ECO:0000313|EMBL:CCZ20640.1};
GN ORFNames=BN766_01585 {ECO:0000313|EMBL:CCZ20640.1};
OS Candidatus Apopatosoma intestinale.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Apopatosoma.
OX NCBI_TaxID=1262966 {ECO:0000313|EMBL:CCZ20640.1, ECO:0000313|Proteomes:UP000018243};
RN [1] {ECO:0000313|EMBL:CCZ20640.1, ECO:0000313|Proteomes:UP000018243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:724 {ECO:0000313|Proteomes:UP000018243};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ20640.1}.
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DR EMBL; CAZP010000129; CCZ20640.1; -; Genomic_DNA.
DR AlphaFoldDB; R5PVS9; -.
DR STRING; 1262966.BN766_01585; -.
DR Proteomes; UP000018243; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000018243};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 95..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 526..717
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 28..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 795..814
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 543..550
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 900 AA; 97545 MW; 972D167EE98547AE CRC64;
MAVNKKKKQA AQEDDFFEYD DAFTINEEDI SGARRRSDRK RGNDTGRGAE RGFEAKKDGA
SAHGTSDKGT RGEDRTKADA EKPKKRKKPA NPSSVGNQIM IAVMAALAIF VGVCFAAAEK
VGVIGGFISE FLPGTFGGAA LLIPFMLLIH ALYWKRDTAS GLRLFRLMFS FAVTVIFSSL
LHVIFIATGS FTVGEKMSVL LKDFYLQGIY YKGGGVVGGL LGTLGVRGLG VPGALIFSIL
FLVIAVILFL GYTPGIVWRR TVFYIMRGIE KKKAEKREKK EREDKARSEE EAAKAAGTAL
VVRKGGIGED ILSGNGITDE PEKEPYDFFS SGTESAPAAQ DEREPIAENI MPVRRTKIKK
QEKPKNDVPS VILAGANGEP AIIPEEPPVP EYQFPPIDLL VYKEQTGGDT QSEMTANAQK
IVSTLGDFNI RTRVIGISRG PAVTRYEIAP ESGTKVAAII NRADDISLSL ASAVRISGVI
PGKSAIGIEV PNKNVSTVYL RTLIDSDEFR NAKSKVTAAL GIDITGRNIL FDIAKMPHLL
IAGATGMGKS VCMNSLIISI LYKAKPDEVK FIFIDPKKVE FNMYNGIPHL LVPVVFDPKK
AAGALHWAVT EMERRYDILE ATGKRNLTQY NEAIKDDPTA EKLPQIVIFI DELADLMLTA
PDDVETSINR IAAKARAAGM HLIIGTQRPS VDVITGTIKA NIPSRIACTV SSMQDSRTIL
DMGGAEKLIG RGDMLFSPVG SMSPTRVQGA YVDEPEILKI VDFLKNQECF ENNETYSREI
SEKIEKEAAR CGQKKGSGAG LAAASSDGDG DDKADPMLDS AIKLAIESGK ISTSLIQRKL
SLGFGRAAKL IDIMEQKGIV SAPDGQKPRT VLITYDQYLE MGMQNPPSQS DESGAGDEPW
//
