ID R5S360_9CLOT Unreviewed; 484 AA.
AC R5S360;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpX {ECO:0000313|EMBL:CCZ41401.1};
GN ORFNames=BN479_01458 {ECO:0000313|EMBL:CCZ41401.1};
OS Clostridium sp. CAG:122.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262773 {ECO:0000313|EMBL:CCZ41401.1, ECO:0000313|Proteomes:UP000017991};
RN [1] {ECO:0000313|EMBL:CCZ41401.1, ECO:0000313|Proteomes:UP000017991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:122 {ECO:0000313|Proteomes:UP000017991};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ41401.1}.
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DR EMBL; CAZY010000109; CCZ41401.1; -; Genomic_DNA.
DR AlphaFoldDB; R5S360; -.
DR Proteomes; UP000017991; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd19497; RecA-like_ClpX; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR004487; Clp_protease_ATP-bd_su_ClpX.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010603; Znf_CppX_C4.
DR NCBIfam; TIGR00382; clpX; 1.
DR PANTHER; PTHR48102:SF7; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR48102; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR Pfam; PF06689; zf-C4_ClpX; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:CCZ41401.1};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Hydrolase {ECO:0000313|EMBL:CCZ41401.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000313|EMBL:CCZ41401.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000017991};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 170..329
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 372..466
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
SQ SEQUENCE 484 AA; 54151 MW; 1403DC8212F91D45 CRC64;
MSDNNNSDNI NASDNNNNND SYEEICYICR RPESKAGKMI HIPNNICICN DCMQKTFDSM
NNMNLNGTFP NMPYMDMFGF GMPNMPGGDN IPKNQKIKKK KAAKEKKKDN IQTGVFDIKH
LPAPHIIKSK LDEYVVGQEF AKKVMSVAVY NHYKRVLSDD IEEDDGIEIE KSNMLMVGPT
GCGKTYLVKT LAKILQVPLA ITDATSLTEA GYIGDDVESV LSKLLAAADN DVEKAEHGII
FIDEIDKIAK KRNTNSRDVS GESVQQGMLK LLEGSDVEVP VGATSKNAMV PLTTVNTRNI
LFICGGAFPE LEKVIKNRLT KQSSIGFEAE LKDKYDNDEN ILSKVTTEDL REFGMIPEFL
GRLPIVFTLQ AMTEDMLAQI LTQPKNAILK QYKKLLALDE VDLKFDDEAV HCIAKKALKK
NTGARALRAI IEDFMLDIMY EIPKDDMIGR VTITDDYINH KGSPVIEMRE SSEAKILTQR
DLIE
//
