ID R5V2Y1_9FIRM Unreviewed; 303 AA.
AC R5V2Y1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Maltose/maltodextrin transport system permease protein {ECO:0000256|RuleBase:RU367050};
GN ORFNames=BN518_01340 {ECO:0000313|EMBL:CCZ77751.1};
OS Roseburia sp. CAG:18.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1262941 {ECO:0000313|EMBL:CCZ77751.1, ECO:0000313|Proteomes:UP000018230};
RN [1] {ECO:0000313|EMBL:CCZ77751.1, ECO:0000313|Proteomes:UP000018230}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:18 {ECO:0000313|Proteomes:UP000018230};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the ABC transporter complex MalEFGK involved in
CC maltose/maltodextrin import. Probably responsible for the translocation
CC of the substrate across the membrane. {ECO:0000256|RuleBase:RU367050}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. MalFG subfamily. {ECO:0000256|ARBA:ARBA00009047,
CC ECO:0000256|RuleBase:RU367050}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU367050}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ77751.1}.
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DR EMBL; CBAP010000021; CCZ77751.1; -; Genomic_DNA.
DR AlphaFoldDB; R5V2Y1; -.
DR Proteomes; UP000018230; Unassembled WGS sequence.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:UniProtKB-UniRule.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-UniRule.
DR GO; GO:0055085; P:transmembrane transport; IEA:UniProtKB-UniRule.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.20.58.370; MalF N-terminal region-like; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR InterPro; IPR035277; MalF_N.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR47314; MALTOSE/MALTODEXTRIN TRANSPORT SYSTEM PERMEASE PROTEIN MALF; 1.
DR PANTHER; PTHR47314:SF1; MALTOSE_MALTODEXTRIN TRANSPORT SYSTEM PERMEASE PROTEIN MALF; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF160964; MalF N-terminal region-like; 1.
DR SUPFAM; SSF161098; MetI-like; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU367050};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Reference proteome {ECO:0000313|Proteomes:UP000018230};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW ECO:0000256|RuleBase:RU367050};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 70..94
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 106..126
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 157..183
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 204..227
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 273..291
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 71..292
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
SQ SEQUENCE 303 AA; 33792 MW; 5F499C21233FBD36 CRC64;
MRKKKNALGY TYLAPALISI LLVTCLPIIY TVILSFTNYN MYHLTDYTFV GLENYLTVFS
GSIKNVFFPV LGWTICFALL STAGSYAMGL ILAILLNNPH MKESKIYRAV LIVPWALPST
IAILAWQGLL NEQYGGINNL LHTIGIAWNV PWLTNPFWAR VGLIIVNVWL GFPYMMNVCL
GGLQAISGEY YEAAKMDGAS KFQCFKSITL PMVTKLSIPL VISSFAANFN NFGNIYMITQ
GGPARVDNQF AGYTDILAST TYKMTTWSNR YELSATFSVL IFIIVGTFTL INMRLSGSFK
EVD
//
