ID   R5VZZ2_9FIRM            Unreviewed;       391 AA.
AC   R5VZZ2;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=NADPH-dependent butanol dehydrogenase {ECO:0000313|EMBL:CCZ86052.1};
GN   ORFNames=BN742_01073 {ECO:0000313|EMBL:CCZ86052.1};
OS   Firmicutes bacterium CAG:631.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1262996 {ECO:0000313|EMBL:CCZ86052.1, ECO:0000313|Proteomes:UP000018035};
RN   [1] {ECO:0000313|EMBL:CCZ86052.1, ECO:0000313|Proteomes:UP000018035}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:631 {ECO:0000313|Proteomes:UP000018035};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCZ86052.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CBAS010000114; CCZ86052.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5VZZ2; -.
DR   STRING; 1262996.BN742_01073; -.
DR   Proteomes; UP000018035; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd08179; NADPH_BDH; 1.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR   InterPro; IPR001670; ADH_Fe/GldA.
DR   InterPro; IPR018211; ADH_Fe_CS.
DR   InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR   InterPro; IPR034802; NADPH_BDH.
DR   PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR11496:SF83; HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00465; Fe-ADH; 1.
DR   SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR   PROSITE; PS00913; ADH_IRON_1; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018035}.
FT   DOMAIN          7..376
FT                   /note="Alcohol dehydrogenase iron-type/glycerol
FT                   dehydrogenase GldA"
FT                   /evidence="ECO:0000259|Pfam:PF00465"
SQ   SEQUENCE   391 AA;  42842 MW;  524E6E65DAB09F28 CRC64;
     MSRFTLPRDI YYGKGCLDVL KTLKGKKAMI VVGGGSMKRF GFLDQVINYL HEAKIEVELF
     ENVEPDPSVE TVMRGAEAMR KFQPDWIVAM GGGSPIDAAK AMWAFYEYPN TTMDDLIIPF
     NFPELRTKAR FLAIPSTSGT ATEVTAFSVI TDYSKGIKYP LADFNITPDV AVVDPTLAET
     MPATLTAHTG MDALTHAIEA YVSTLHSVFT DPLALKAIHM VFDYLPASYR GDMAAREQMH
     YAQCLAGMAF SNALLGIVHS MAHKTGAAFS TGHIPHGCAN AIYLPYVIKF NAKAGATRYA
     EIARSIGLTG ASDEELVEKL CAKIDDYNVQ LNIPKTLKEF GILEDEFKEK VAHIAELAVG
     DACTGSNPRP ITPKEMEKLL TCAYYGTEVD F
//