ID R5YEV6_9FIRM Unreviewed; 577 AA.
AC R5YEV6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Type II secretion system protein E (GspE) {ECO:0000313|EMBL:CDA25395.1};
GN ORFNames=BN528_02173 {ECO:0000313|EMBL:CDA25395.1};
OS Roseburia sp. CAG:197.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1262943 {ECO:0000313|EMBL:CDA25395.1, ECO:0000313|Proteomes:UP000018336};
RN [1] {ECO:0000313|EMBL:CDA25395.1, ECO:0000313|Proteomes:UP000018336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:197 {ECO:0000313|Proteomes:UP000018336};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GSP E family.
CC {ECO:0000256|ARBA:ARBA00006611}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDA25395.1}.
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DR EMBL; CBBL010000206; CDA25395.1; -; Genomic_DNA.
DR AlphaFoldDB; R5YEV6; -.
DR Proteomes; UP000018336; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd01129; PulE-GspE-like; 1.
DR Gene3D; 3.30.450.90; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.300.160; Type II secretion system, protein E, N-terminal domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001482; T2SS/T4SS_dom.
DR InterPro; IPR037257; T2SS_E_N_sf.
DR InterPro; IPR007831; T2SS_GspE_N.
DR PANTHER; PTHR30258:SF2; BACTERIOPHAGE ADSORPTION PROTEIN B; 1.
DR PANTHER; PTHR30258; TYPE II SECRETION SYSTEM PROTEIN GSPE-RELATED; 1.
DR Pfam; PF05157; MshEN; 1.
DR Pfam; PF00437; T2SSE; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF160246; EspE N-terminal domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00662; T2SP_E; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000018336}.
FT DOMAIN 390..404
FT /note="Bacterial type II secretion system protein E"
FT /evidence="ECO:0000259|PROSITE:PS00662"
FT COILED 154..181
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 577 AA; 64167 MW; 506F6BD64E742A7B CRC64;
MDKPIGFGRK KRLGDLLVEA GTITQDQLTQ ALNVQKTEKK GQRLGDVLMD LGFTDEKQIM
KALCSQLKLQ PVDLSNIRIP EEITKLTEEA VLRKHNLIPF QFHEKNPNVI KVAMSDPLDI
RAMDDISIIT GLQIERYVAT PGDIAAAIDR YYGNAEALRV AEQYTREREE QNKNKNVEAE
DESNVQQAPI VKLLGQIIEQ AVHKRTSDIH IEPMENQVRI RFRVDGVLHE AMRHDISLHA
ALIARIKIVS GLDISEKRRP QDGRATSIVD RQEYDIRVSI LPTVYGEKVV MRLAKKKALT
MDKKELGFPD DELAKFDKIL SHPNGMILVT GPTGSGKSTT LYTALNELNG EGVNIITVED
PVEANVAGIN QVQVNEKAGL TFSSALRSIL RQDPDIIMIG EIRDQETAAI AVKASITGHL
VVSTLHTNSA ASTLTRLADM EVENYLIADS VVGVIAQRLV RRVCPNCGVV HEASPADLKT
LGLQNLNRKV MLRYPGHKEC VRCGGTGYFG RIGIYEIMPI TNDLRQAINQ GKNADELEAI
ALRHGMKTLR MSAIEYALKG ITTVEEVRRV AFEDEDE
//
