ID R6CCU8_9CLOT Unreviewed; 622 AA.
AC R6CCU8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=cellulase {ECO:0000256|ARBA:ARBA00012601};
DE EC=3.2.1.4 {ECO:0000256|ARBA:ARBA00012601};
GN ORFNames=BN687_01233 {ECO:0000313|EMBL:CDA69331.1};
OS Clostridium sp. CAG:510.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262816 {ECO:0000313|EMBL:CDA69331.1, ECO:0000313|Proteomes:UP000018120};
RN [1] {ECO:0000313|EMBL:CDA69331.1, ECO:0000313|Proteomes:UP000018120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:510 {ECO:0000313|Proteomes:UP000018120};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|RuleBase:RU361153}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDA69331.1}.
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DR EMBL; CBCI010000108; CDA69331.1; -; Genomic_DNA.
DR AlphaFoldDB; R6CCU8; -.
DR STRING; 1262816.BN687_01233; -.
DR Proteomes; UP000018120; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR31297:SF17; ENDOGLUCANASE; 1.
DR PANTHER; PTHR31297; GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B; 1.
DR Pfam; PF00150; Cellulase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW Hydrolase {ECO:0000256|RuleBase:RU361153};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018120};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 97..395
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
SQ SEQUENCE 622 AA; 69007 MW; D88269B1AE4E1151 CRC64;
MEKKKGNALP VVLFAVAGIA LIALVIMILM VLKVGPFAEG SAKEKERVLH TSANGIETMD
NGYMRKDLSA SELTVLMGNG INLGNTMEAY GRISLGTEAP VSSYETFWSQ PVTTQEMITG
MKNAGFDTLR IPVAWTNAMD YESGDYTIRE DYLNRVEEII NYALNENMYV VINDHWDGSW
WGMFGSASEE TRQKAWDLYT SMWTQIAERY KEYSDYLIFE SANEELGNRL NDTDVAADSG
TLSADECYEM TLKINQKFVD IVRGTGGNNE SRFLLIAGYN TDVDMTTDDR YIMPTDPANE
VNKLILSVHY YTPWGYCGNE SLSLWGTKRN YGEMNSLLES LTKFTDQGYG VIIGEYGVLV
KSDGTLKKNA ALYYKNFLDN CDLYNFCPLL WDCNNLYNRQ DCKIIDDEIA ALYKERAYAN
EAAMTDEEKA ARPDKIKAEM DQAYADAPAA FDDGAIDLDD STSVAWIMIN SSDWNVMYSV
GDVYDPGAKT DGLVATDVEI TGEGTYTVSL DFTGVPGGYA NGMAFSALAI GNGELLYPGY
TVNITEVLVN GEPYTLTAKP YTTSDDARCT RVNLYNEWVT QVPGDARTPD GDTTGISPVI
VDNADLTHME TLSITFEYAP GK
//
