ID R6CER3_9FIRM Unreviewed; 1918 AA.
AC R6CER3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=DNA helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=BN718_00121 {ECO:0000313|EMBL:CDA74120.1};
OS Ruminococcus sp. CAG:579.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1262963 {ECO:0000313|EMBL:CDA74120.1, ECO:0000313|Proteomes:UP000018387};
RN [1] {ECO:0000313|EMBL:CDA74120.1, ECO:0000313|Proteomes:UP000018387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:579 {ECO:0000313|Proteomes:UP000018387};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDA74120.1}.
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DR EMBL; CBCK010000201; CDA74120.1; -; Genomic_DNA.
DR STRING; 1262963.BN718_00121; -.
DR Proteomes; UP000018387; Unassembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR021754; DUF3320.
DR InterPro; IPR025103; DUF4011.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049468; Restrct_endonuc-II-like_dom.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF11784; DUF3320; 1.
DR Pfam; PF13195; DUF4011; 1.
DR Pfam; PF18741; MTES_1575; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018387}.
FT DOMAIN 667..789
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1304..1343
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1364..1554
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT DOMAIN 1606..1699
FT /note="Restriction endonuclease type II-like"
FT /evidence="ECO:0000259|Pfam:PF18741"
FT DOMAIN 1751..1800
FT /note="DUF3320"
FT /evidence="ECO:0000259|Pfam:PF11784"
SQ SEQUENCE 1918 AA; 212011 MW; 6BE08D74DA59D1DD CRC64;
MDNIVSVSGN INASINFAMQ QNYVPVIRDL VVANESDAVL ENIDLKISFE PEFAKTFTYH
VENIPANGSV EISPVKIATN TDFLFSLTEK MIGNITVDVL RGDENIFTYQ DQIELLAYDQ
WSGLAVMPEI IAAFVTPNHP AVSAVVHDAS LFLKKWKDDP AFTGYQTQNP NNVKLQMAAI
YAALAQQKII YNNPPASYEM SGQRVRLPHS VLEQKLGTCL DLALLYASCI EAVGLHPLLV
FLKGHAFCGC WLESETFADC CVDDISALEK RIAADAEEIL LVECTDFVDG RTADFDRALK
HGKDHLNDVS NFNCVVDIQR SRGSGIRPIP LRPELSCSGI QLAEENDKPR EVRAPSELSS
SMLGRVAEGS DKPVTKINIW ERKLLDFSLR NSLLNFRVTK STMQIMTADL AKLEDELASG
SDLRIMEIPS EWTVSVRDAK IFEIENEKDL ITNIAEAEFK SKRIRTFLSE KDLDAALKNL
YRSAKVSMEE NGSNTLFLSL GLLRWFESDI SERPRYAPLV LIPIDIVRNS RNKGYVIRSR
QEETQINVTL LEYLRQDHGI KITGLDPLPL DEQGIDLPLV FNTIRQAIMG KKRWNIEEYA
FIGLFSFSQF VMWNDLRNRA DELKENKVVS SLIEGRLTYS PEDIDLTPEN IDSAPDLANM
AVPMSADSSQ LAAIAAAGRG QSFVLHGPPG TGKSQTITNM IANALYNDKT VLFVAEKMAA
LNVVQKRLEN LGLDPFCLEL HSNKTNKSSV LAELNRALEV GRIKSPEEYA AEADKLSGQK
RKLNDTINAL HEKRSCGMSL FDTISAYERA ADEQGKISFS HAAPAELTKD QLALYAELVH
KYSVAIAETG RFSEFPLSGV GVTAYSIDQR DRFRALADEL SEKTNAAARH AHTLAEAYGY
HGALDKPSVK MLAEIFAAAR MEGELLPALL AAPHYDVLFE KITQTVALGK QYSALCAEIG
ASFEKSVFDY PAAEARQRCK QAEASWFLPK ALGLSKLVKA LKLRAKDPAA VKKTDLAAIL
DKLCAAGEMR ETLRSLPSDV AATMTGLYMN EQTDWNALEK ASAKTAAVMS AIRAKDGVLP
AEIAEKLAAA NCDAEGAALA DCLEKLAAFE KEFAVNISEL DGQSDWLSAA ADRLRVYADN
ADKLRYAAEF NTADKALADS GLACVSESYR AGNVSSENVE TAFSCALHYQ LALAMIHADE
RLKGFSSNSL NDLIVQFKLE TERFSRLTVQ ELAARLSAKI PVAGSACSAA SEMGILKRAI
KSGGRMISLR SLFDKIPTLL RRLCPCMLMS PISVAQYIDP SFPKFDLVIF DEASQLPTAE
AAGTIARGEN VVIVGDPKQL PPTNFFSSNR IDEENSDKED LESLLDDCLA ISMPQEYLKW
HYRSRHESLI AYSNMKYYDN KLLTFPSNND LISKVSIVHP EGFYDKGKTK QNKAEARAVV
DEIIRRLSDE KLRGESIGVV TFSSVQQNLI DDMLCEEWEK HPELEELDQR SAEPIFIKNL
ENVQGDERDV ILFSVGYGPD QSGNVSMNFG PLNREGGWRR LNVAISRARK AMIVYSVLRP
EQIDLSRTRS EGVAGLKGFL EFAEKGRLAV IQHDSAAPSA DSTVAESIAK AITEMGYDVK
CAIGSSEFKV DIGVIDPENE EEYILGILLD GSAENSTAQD KFVLQPGVLK GLGWNLIRIW
TLDWFDDRQR VLRSIKAAIE NVPKQEKSVK VRVKPTVFAA ATFEKEDISK LAATAREDYI
TAEIGVIGTS DEYYLPQNKR RIKEIVEKII AVEAPISRKL LMKKVLSAWS ITRGGARVES
IFTDVMSSVS ATATQDEDRV FIWRDGQRPE EYSAYRADSE SAKRTADNIP SEEILCAASE
VLSEQISLSE PDLIKETAKK FGFARAGGVI ESTIGYAVRK GIESGKLAKS DKGRVTAV
//
