ID R6EKA6_9FIRM Unreviewed; 749 AA.
AC R6EKA6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDA97096.1};
GN ORFNames=BN538_00733 {ECO:0000313|EMBL:CDA97096.1};
OS Lachnospiraceae bacterium CAG:215.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1262985 {ECO:0000313|EMBL:CDA97096.1, ECO:0000313|Proteomes:UP000018007};
RN [1] {ECO:0000313|EMBL:CDA97096.1, ECO:0000313|Proteomes:UP000018007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:215 {ECO:0000313|Proteomes:UP000018007};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDA97096.1}.
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DR EMBL; CBCV010000040; CDA97096.1; -; Genomic_DNA.
DR AlphaFoldDB; R6EKA6; -.
DR Proteomes; UP000018007; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 38..141
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 156..256
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 265..554
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 749 AA; 86316 MW; 6760043C2CFD8651 CRC64;
MEEMLINDGW SFHKENEAEE NISIPHTYNS ADGQSGTSMW RGKGYYKREL VFREEDREKT
IYLEIGAAAM RSTVYINGKN IYENTCPYAM YRVALNEHIT EGINLLELVV DNTATDAIYP
QMADFSFYGG IYRDVKLVYA PKVHFDYLDG SRSGVQVRTK KLDEGKWEVK AEGCVINEGS
MCAGQVKISL VDKENIVSEK TIQFSFAEKT PFSVQQEISD PHLWMGTEDP YLYQVRIEIS
TEEGCMEERE IQTGFREIEI DPERGMFLNG KHIKLHGVAR HQDFGGVGNA VSREQMEEDM
ALIKELGANS VRLSHYQHDD YFYRRCDEEG ILVWAEVPFI SILSDNKKAD ENIREQMRRL
ILQCGNHTSI YCWGVQNEIT IGGENTEIHA SVESMAAYTK ELDADRYTAE ANIYSVANES
ALNRMTELVG YNLYYGWYYD EITGLQKRLD EFHAACPDIP LLVTEYGVDT NPQYHSYQPK
TKDYSEEFQL LFSDNALKAF EEREYFIGSY VWNLCDFGSA SRDEGGKQGQ NQKGLVTIDR
KIKKDAYYLY KAYWSKECFV KLAGSRFLNR HLEENTITVL SNLNRLILYV NGQKIAETDN
VDPMTQFSVQ LQMGKNEITV KGFDKENREY ADAQILYRVE NPEKSYEYVP KEQGKNVINW
FEKFDLESAD KEEIVIDSNF YSSGDKLGDI MKNPDGEKIV LKYFGEMKDH PKFGMMKVMT
LDAMGKLKNL GIPKELILVI NKELQKIKK
//
