ID R6FSM5_9FIRM Unreviewed; 389 AA.
AC R6FSM5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=ribose-phosphate diphosphokinase {ECO:0000256|ARBA:ARBA00013247};
DE EC=2.7.6.1 {ECO:0000256|ARBA:ARBA00013247};
GN ORFNames=BN525_00397 {ECO:0000313|EMBL:CDB12454.1};
OS Eubacterium sp. CAG:192.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1262883 {ECO:0000313|EMBL:CDB12454.1, ECO:0000313|Proteomes:UP000017943};
RN [1] {ECO:0000313|EMBL:CDB12454.1, ECO:0000313|Proteomes:UP000017943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:192 {ECO:0000313|Proteomes:UP000017943};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ribose-phosphate pyrophosphokinase family.
CC {ECO:0000256|RuleBase:RU004324}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB12454.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CBDB010000053; CDB12454.1; -; Genomic_DNA.
DR AlphaFoldDB; R6FSM5; -.
DR STRING; 1262883.BN525_00397; -.
DR Proteomes; UP000017943; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
DR GO; GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 2.
DR InterPro; IPR029099; Pribosyltran_N.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR005946; Rib-P_diPkinase.
DR NCBIfam; TIGR01251; ribP_PPkin; 1.
DR PANTHER; PTHR10210:SF32; RIBOSE-PHOSPHATE DIPHOSPHOKINASE; 1.
DR PANTHER; PTHR10210; RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF13793; Pribosyltran_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 2.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:CDB12454.1};
KW Nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022727,
KW ECO:0000256|RuleBase:RU004324}; Transferase {ECO:0000313|EMBL:CDB12454.1}.
FT DOMAIN 16..165
FT /note="Ribose-phosphate pyrophosphokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13793"
FT DOMAIN 192..307
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 389 AA; 44074 MW; A71267FDAA464B14 CRC64;
MAIEKFIESI PVGPLAIVAL SGSKALGETV DAYISDWRSE RIEAKESPIT FKGYVKDSYL
LDVDTPRFGT GEAKCTLRDT VRGTDLYIID DVTNYSVEYT VCGHKNHMSP DDHYADIKRV
IAAAAGKAKK ITVIMPFLYE SRQHRRSSRE SMDCAVMLQE LVSMGVDNIL TFDAHDPRVN
NAIPISGFES IMPTYQYIKN LLRNVDDLII DDDHLMVISP DEGAMSRVVY FANALGINMG
MFYKRRDFTQ VVDGRNPIVA HEYLGESVEG KDVLIIDDMI SSGDSMLDVA RQLKKRKAKR
VFVASTFGLF TNGLERFDEA YADGTIYRIM TTNCIYQTPE LLSREWYINV DVAKYTAYFI
DRLNHDSSIS DLLNPYKKIE KCVEAYKNR
//
