ID R6FV47_9FIRM Unreviewed; 571 AA.
AC R6FV47;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Beta-galactosidase {ECO:0000256|ARBA:ARBA00013303};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
DE AltName: Full=Lactase {ECO:0000256|ARBA:ARBA00032230};
GN ORFNames=BN525_00828 {ECO:0000313|EMBL:CDB12911.1};
OS Eubacterium sp. CAG:192.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1262883 {ECO:0000313|EMBL:CDB12911.1, ECO:0000313|Proteomes:UP000017943};
RN [1] {ECO:0000313|EMBL:CDB12911.1, ECO:0000313|Proteomes:UP000017943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:192 {ECO:0000313|Proteomes:UP000017943};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB12911.1}.
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DR EMBL; CBDB010000188; CDB12911.1; -; Genomic_DNA.
DR AlphaFoldDB; R6FV47; -.
DR STRING; 1262883.BN525_00828; -.
DR Proteomes; UP000017943; Unassembled WGS sequence.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR004199; B-gal_small/dom_5.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032312; LacZ_4.
DR PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR46323:SF2; BETA-GALACTOSIDASE; 1.
DR Pfam; PF02929; Bgal_small_N; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF16353; LacZ_4; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SMART; SM01038; Bgal_small_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 296..565
FT /note="Beta galactosidase small chain/"
FT /evidence="ECO:0000259|SMART:SM01038"
SQ SEQUENCE 571 AA; 65506 MW; 0D17D3BB14A32393 CRC64;
MYERDKNHPA ILMWSLGNES YAGTVLEATS KYLHAKDNTR LVHYEGVVWN REFDHITDME
SRMYAKPQDV VEYLENNPKK PYINCEYTHA MGNSCGGMHL YTDLEDKYDM YQGGFIWDYI
DQAIEVEENG KKVLKYGGDF GERATDYCFC TDGIIYANRT PSPKVQEVKY LYQNIKMNIF
ENEIEIDNQN LFTNTNKYVF VLEIIQKETS ICKKEYSFDV EPGEKKRFQL NIPETIGLTR
NEDYIYNMSI QLKGDEKWAE KGFEIAKEQY VFEGVCNTEK TAINNLEVIN GDVNIGVRGN
DFFAMFSKQE AGIISLVYSD KEYITRAPKP TFVRAYTDND KGCGLDFQYA IWDKAGKTAK
CTGFAKDELE EGIKITYDYV LPIEGKSCTI SYLVYGDGSI DVDFKLKGED EFSIPLYGME
FKLPKEFVNV KYFGNGPEEN YQDRNKGAKL GVYETTAADN MSSYLIPQEC GNRTGIRYME
ITDETQEGIR FSYVDKPIEG SVLPYSAAEL ENAMHIEELP QSSYTWVRVL GQQMGVGGDD
SWGAPVQEIY TIPKSKVHEF KFNISPAKQR S
//
