ID   R6KI70_9BACE            Unreviewed;       611 AA.
AC   R6KI70;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Pyruvate carboxyltransferase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BN506_04102 {ECO:0000313|EMBL:CDB73170.1};
OS   Bacteroides cellulosilyticus CAG:158.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1263038 {ECO:0000313|EMBL:CDB73170.1, ECO:0000313|Proteomes:UP000018191};
RN   [1] {ECO:0000313|EMBL:CDB73170.1, ECO:0000313|Proteomes:UP000018191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:158 {ECO:0000313|Proteomes:UP000018191};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB73170.1}.
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DR   EMBL; CBEB010000405; CDB73170.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6KI70; -.
DR   Proteomes; UP000018191; Unassembled WGS sequence.
DR   GO; GO:0004736; F:pyruvate carboxylase activity; IEA:UniProt.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   CDD; cd06850; biotinyl_domain; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR001882; Biotin_BS.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR003379; Carboxylase_cons_dom.
DR   InterPro; IPR000891; PYR_CT.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   PANTHER; PTHR45266; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR   PANTHER; PTHR45266:SF3; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR   Pfam; PF00364; Biotin_lipoyl; 1.
DR   Pfam; PF00682; HMGL-like; 1.
DR   Pfam; PF02436; PYC_OADA; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR   SUPFAM; SSF51230; Single hybrid motif; 1.
DR   PROSITE; PS00188; BIOTIN; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS50991; PYR_CT; 1.
PE   4: Predicted;
KW   Biotin {ECO:0000256|ARBA:ARBA00023267};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018191}.
FT   DOMAIN          4..268
FT                   /note="Pyruvate carboxyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS50991"
FT   DOMAIN          526..611
FT                   /note="Lipoyl-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50968"
SQ   SEQUENCE   611 AA;  67762 MW;  E601FBC6BAB24AA1 CRC64;
     MKKEIKFSLV FRDMWQSAGK YVPRVDQLVK VAPAIVEMGC FARVETNGGG FEQVNLLFGE
     NPNKAVRAWT KPFHEAGIQT HMLDRALNGL RMSPVPADVR KLFYKVKKVQ GTDITRTFCG
     LNDVRNIAPS ITYAKEAGMI SQCSLCITHS PIHTVEYYTN MALELIKLGA DEICVKDMAG
     IGRPVSLGKI VANIKAAHPE IPIQYHSHAG PGFNMASILE VCEAGCDYID VGMEPLSWGT
     GHADLLSVQA MLKDAGFQVP EVNMEAYMKV RALIQEFMDD FLGLYISPKN RLMNSLLIGP
     GLPGGMMGSL MADLESNLES INKYKAKRNL PFMTQDQLLI KLFNEVAYVW PRVGYPPLVT
     PFSQYVKNLA MMNVIAMEKG KERWGMIADD IWDMLLGKAG KLPGTLAPEI IEKAEREGRK
     FFTGNPQDNY PDALDKYRKM MKENKWDLGE DDEELFEYAM HPAQYEAYKS GKAKEDFLAD
     VEKRKAELNK SPLDDAKPKT LTVQVDGQAY RVTVAYGDID LPADATAKVE APVGEGQDVP
     APLEGKFFLT KNAQETPIKV GDKVKKGDLL CYIEAMKTYN AIRADFDGTV TAICATSGDS
     VAEDDVLMKI G
//