ID R6M538_9CLOT Unreviewed; 585 AA.
AC R6M538;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Cell wall hydrolase/autolysin {ECO:0000313|EMBL:CDB90979.1};
GN ORFNames=BN565_00651 {ECO:0000313|EMBL:CDB90979.1};
OS Clostridium sp. CAG:253.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262785 {ECO:0000313|EMBL:CDB90979.1, ECO:0000313|Proteomes:UP000018071};
RN [1] {ECO:0000313|EMBL:CDB90979.1, ECO:0000313|Proteomes:UP000018071}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:253 {ECO:0000313|Proteomes:UP000018071};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB90979.1}.
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DR EMBL; CBEI010000201; CDB90979.1; -; Genomic_DNA.
DR AlphaFoldDB; R6M538; -.
DR STRING; 1262785.BN565_00651; -.
DR Proteomes; UP000018071; Unassembled WGS sequence.
DR GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:InterPro.
DR GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR CDD; cd02696; MurNAc-LAA; 1.
DR Gene3D; 3.30.457.10; Copper amine oxidase-like, N-terminal domain; 1.
DR Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 1.
DR InterPro; IPR012854; Cu_amine_oxidase-like_N.
DR InterPro; IPR036582; Mao_N_sf.
DR InterPro; IPR002508; MurNAc-LAA_cat.
DR PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR Pfam; PF01520; Amidase_3; 1.
DR Pfam; PF07833; Cu_amine_oxidN1; 1.
DR SMART; SM00646; Ami_3; 1.
DR SUPFAM; SSF55383; Copper amine oxidase, domain N; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CDB90979.1}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..585
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004425788"
FT DOMAIN 458..575
FT /note="MurNAc-LAA"
FT /evidence="ECO:0000259|SMART:SM00646"
SQ SEQUENCE 585 AA; 65551 MW; 86EF6FE5CA1C6EE4 CRC64;
MNKFSKISKA FFIAGITAMC LSIAPKPAIA NASVSIEQNN DGNYINIEND SSLKAVYNNV
TYSNETFPAI RVDDVWMVPV KEFLQDILGC TYSYDENEGT LFISNNYGNA SVSCVVGSKE
LSVGSSVVGM DLPVMKAKNT EDNAKKTIYV PASKVIQNLG YGYDSSATEI SVTDNIKLYE
NSKQTEYENQ YSNAINSIIY TKNLSGNDIV NITALNDLDE NKVKENTDYN SIEYIYADTK
NLLGDIDKSF ENGVVTEIKI WEEENNTHLK ITFDGRYVVS KQILANTFSV ILEKGSFSIK
ALIPDGVDAK KITATDRYWN KQFYIIVPGN HVSFYKKYIP INNSSVIQKI NVNKTADGNN
TRIVVTTTKL QGYKITNEDG YFTVKIGAPK KIYKNIILLD AGHGGKDSGA SYKNLYEKKL
NLEIIYTRAR KYFEANNSNV KAYWTRHDDT FINLYTRPKL SKTYSADMFM SLHMNSAGNR
LANGTEVYYS SKNNKVTSTG LYSKKMASMM LNSILDGINA KNRGVRQAGF VVNKYNTVPS
ILVELGFITG NKDYPNLKKA AYREKAAKAL YNGVEKIFKK YPTKR
//
