ID R6NVM6_9FIRM Unreviewed; 237 AA.
AC R6NVM6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Putative acyltransferase {ECO:0000313|EMBL:CDC10306.1};
GN ORFNames=BN662_01611 {ECO:0000313|EMBL:CDC10306.1};
OS Roseburia sp. CAG:45.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1262947 {ECO:0000313|EMBL:CDC10306.1, ECO:0000313|Proteomes:UP000018173};
RN [1] {ECO:0000313|EMBL:CDC10306.1, ECO:0000313|Proteomes:UP000018173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:45 {ECO:0000313|Proteomes:UP000018173};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Converts lysophosphatidic acid (LPA) into phosphatidic acid
CC by incorporating acyl moiety at the 2 position.
CC {ECO:0000256|ARBA:ARBA00037183}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-
CC sn-glycero-3-phosphate + CoA; Xref=Rhea:RHEA:19709,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57970, ChEBI:CHEBI:58342,
CC ChEBI:CHEBI:58608; EC=2.3.1.51;
CC Evidence={ECO:0000256|ARBA:ARBA00001141};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC10306.1}.
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DR EMBL; CBET010000033; CDC10306.1; -; Genomic_DNA.
DR AlphaFoldDB; R6NVM6; -.
DR Proteomes; UP000018173; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd07989; LPLAT_AGPAT-like; 1.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR10434; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE; 1.
DR PANTHER; PTHR10434:SF60; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE LPAT1, CHLOROPLASTIC; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:CDC10306.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018173};
KW Transferase {ECO:0000313|EMBL:CDC10306.1}.
FT DOMAIN 70..186
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 237 AA; 27765 MW; C7175105BAA8B3BF CRC64;
MLRFIYVILM NLFRAPYIIP KMRKWADHPE KYSEEERYKL VRHVIYLMKR SGKIKTVAYG
EENLPKEGGY VMYPNHQGKY DALGIISTHK EPCSLVMDEA KSHTILVSEF VDLLQGKRLI
KDNVRQALKI ITEVSEDVKN GKKYILFPEG GYEFNNRNRV CDFKAGSFKS AIKAHVPIVP
IALIDSYKVF NSFYLWPITT QVHYLEPIYY EEYKDMKSKE IAELVKQRIQ DKISSIL
//
