ID R6RNG3_9FIRM Unreviewed; 726 AA.
AC R6RNG3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Ferrous iron transporter FeoB {ECO:0000313|EMBL:CDC44581.1};
GN ORFNames=BN788_01523 {ECO:0000313|EMBL:CDC44581.1};
OS [Eubacterium] siraeum CAG:80.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Oscillospiraceae incertae sedis.
OX NCBI_TaxID=1263080 {ECO:0000313|EMBL:CDC44581.1, ECO:0000313|Proteomes:UP000018142};
RN [1] {ECO:0000313|EMBL:CDC44581.1, ECO:0000313|Proteomes:UP000018142}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:80 {ECO:0000313|Proteomes:UP000018142};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC44581.1}.
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DR EMBL; CBFJ010000060; CDC44581.1; -; Genomic_DNA.
DR AlphaFoldDB; R6RNG3; -.
DR Proteomes; UP000018142; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR Gene3D; 1.10.287.1770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011640; Fe2_transport_prot_B_C.
DR InterPro; IPR041069; FeoB_Cyto.
DR InterPro; IPR030389; G_FEOB_dom.
DR InterPro; IPR011642; Gate_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43185:SF1; FE(2+) TRANSPORTER FEOB; 1.
DR PANTHER; PTHR43185; FERROUS IRON TRANSPORT PROTEIN B; 1.
DR Pfam; PF07664; FeoB_C; 1.
DR Pfam; PF17910; FeoB_Cyto; 1.
DR Pfam; PF02421; FeoB_N; 1.
DR Pfam; PF07670; Gate; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018142};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 167..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 463..483
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 526..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 621..643
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..678
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 684..709
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..41
FT /note="FeoB-type G"
FT /evidence="ECO:0000259|Pfam:PF02421"
FT DOMAIN 59..146
FT /note="FeoB cytosolic helical"
FT /evidence="ECO:0000259|Pfam:PF17910"
FT DOMAIN 362..456
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 466..518
FT /note="Ferrous iron transport protein B C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07664"
FT DOMAIN 524..651
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
SQ SEQUENCE 726 AA; 79098 MW; 57898A0D3F370409 CRC64;
MMDIVKKNGD KINIEELSRE LGCKVVEISA LKGTGIKEAA DAAVEAAKNG KTVPMHTFSG
PVEHTIAHIE EAAVHNMPEE QQRWYAIKLF ERDDKVIEKL NLDSAVMAHI DEDIKNVEKE
LDDDAESIIT NERYVYIAEI IKGCYKKKSA GKLTTSDKID KVVTNRFAAL PIFAVIMFLV
YYISMVTVGT AATDWANDGL FGDGWHLFGI GSADYEDASG AYSDALEAVN GFVTIEPDSE
DFEPGTALET LKSYKPEGEN PSVQIDVEDE ETLEVSQLTV YYKEIPANAD KDTTLGITYL
DAVKYFEEGG ESAFEEPDPA SYGVWVPGIP VLIEQGLDAV NCVDWLKGLI LDGIVAGVGA
VLGFVPQMLV LFILLAILEA CGYMARIAFV LDRIFRKFGL SGKSFIPILV GTGCGIPGIM
ASRTIENERD RRMTIMTTTF IPCGAKQPFI AMIAGAIFGG SPWIATGAYF LGMAAIIVSG
IILKKTKMFA GDPAPFVMEL PAYHIPTVGN VLRSMWERGW SFIKKAGTII LLSTIVVWFT
SFFGWVDGAF TMLDESQMDC SILANIGKAI CWIFAPLGWG DWQATVAAVT GLVAKENIVA
TMGILYGSGD ATVWQTLASS FTAVTGMSFL VFNLLCAPCF AAMGAIKREM NNAKWFWFAI
GYECGFAYVI ALMINYFGKL FTGALAGAGD IIGLIVAFLI LAALIYLLVR PYKESKKLGV
KVKVTK
//
