ID   R6RNM3_9FIRM            Unreviewed;       688 AA.
AC   R6RNM3;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Putative stage V sporulation protein D {ECO:0000313|EMBL:CDC36017.1};
GN   ORFNames=BN606_00391 {ECO:0000313|EMBL:CDC36017.1};
OS   Butyrivibrio sp. CAG:318.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Butyrivibrio; environmental samples.
OX   NCBI_TaxID=1262761 {ECO:0000313|EMBL:CDC36017.1, ECO:0000313|Proteomes:UP000018075};
RN   [1] {ECO:0000313|EMBL:CDC36017.1, ECO:0000313|Proteomes:UP000018075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:318 {ECO:0000313|Proteomes:UP000018075};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC36017.1}.
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DR   EMBL; CBFF010000011; CDC36017.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6RNM3; -.
DR   STRING; 1262761.BN606_00391; -.
DR   Proteomes; UP000018075; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018075};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          63..220
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          267..591
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
FT   REGION          626..688
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        666..688
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   688 AA;  76342 MW;  B02ECC1734A8011A CRC64;
     MAVRRRKSIK FTTLMQKKLL IIFMIVMTLL IVLSVVIIRI NASKGYEYSK AVYDNFNYSS
     RTIPARRGDI TDRNGTVIAY SSKVYNLIID AKVLLSDATY REPTVEALLQ YFDLDEKELN
     DYIDDNAKSK ESGGKIDSYK RMLSELTDKD IEEFTNKMNE KNSLIKGVWF EDEYKRIYPY
     SSFACDLMGF ASNANGGELG IENNYNDELS GTDGRIYGYI NDSSYEANRR NAINGNTVVS
     TIDYTIQNII EQAIKDFNDE YGSKSTSVIV ADPNTMEILG MADYPVFDLN NPRDLTSIYS
     AEELEAFTDD EFKDALYKVW SNYCVSSIYE PGSVFKAFTI AEALDEKKAD LKDVYTCDGK
     GVYNSSTILC HGGVGHGDLT LSGALTESCN DALMQISMML GAKTFCRYLD DYKFGSKTGI
     DLPGEENGLL IEESTMMDVD LATNSFGQNL NVTMAQMVAT FASLINGGYY YQPHVVKQIL
     SESGEPVKTI NPTLVTQTVS SDTSHTMREM MRAVVDYGTG GYVHMDGYSI GGKTGTAEKA
     GRDKTEYVIS FMGFAPAENP EVLVYVVIDT PDCEEYNTSW SAQVLARAIM EKLLPYMGIQ
     PDNADYDADI YLDADKLDKK VVKPEINANP ASNPAQTPSE SDAQPDDDND TADKPDNEDE
     TPADTSGQDE TPAETPGQDE TPAAKQQE
//