ID   R6S243_9FIRM            Unreviewed;      1151 AA.
AC   R6S243;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Beta-galactosidase/beta-glucuronidase {ECO:0000313|EMBL:CDC49396.1};
GN   ORFNames=BN788_00911 {ECO:0000313|EMBL:CDC49396.1};
OS   [Eubacterium] siraeum CAG:80.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Oscillospiraceae incertae sedis.
OX   NCBI_TaxID=1263080 {ECO:0000313|EMBL:CDC49396.1, ECO:0000313|Proteomes:UP000018142};
RN   [1] {ECO:0000313|EMBL:CDC49396.1, ECO:0000313|Proteomes:UP000018142}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:80 {ECO:0000313|Proteomes:UP000018142};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC49396.1}.
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DR   EMBL; CBFJ010000217; CDC49396.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6S243; -.
DR   Proteomes; UP000018142; Unassembled WGS sequence.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd04084; CBM6_xylanase-like; 2.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 3.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR005084; CMB_fam6.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR040605; Glyco_hydro2_dom5.
DR   InterPro; IPR006101; Glyco_hydro_2.
DR   InterPro; IPR023232; Glyco_hydro_2_AS.
DR   InterPro; IPR006103; Glyco_hydro_2_cat.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR   Pfam; PF03422; CBM_6; 1.
DR   Pfam; PF18565; Glyco_hydro2_C5; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02836; Glyco_hydro_2_C; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   PRINTS; PR00132; GLHYDRLASE2.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 3.
DR   PROSITE; PS51175; CBM6; 1.
DR   PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023001};
KW   Cellulose degradation {ECO:0000256|ARBA:ARBA00023001};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023001};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018142}.
FT   DOMAIN          1024..1147
FT                   /note="CBM6"
FT                   /evidence="ECO:0000259|PROSITE:PS51175"
SQ   SEQUENCE   1151 AA;  130317 MW;  82BC432BD87E7D29 CRC64;
     MKKRRILFND NWRFTLTEPD SDGKTLENAH WYNVEIPHDW LIGDTSNLYK SGCGWYEKYF
     TVDALGEDDC YILIFDGVYM DTTVYVNDKE VGKWKYGYTT FSFDITDALK NGENRILVRV
     NHKSPNTRWY SGAGIYRNVW LRKTSRRHIV ENGVYISAKC SDTDRREHGK WKTTVQISLS
     DTVCGLISYT LRDPEDREVY VCERRLCGKN DKLVFYMDAP KLWDIITPNL YTLSVILYDD
     NGNRLDDTVE KFGFRTTKFS ANEGFLLNGM HLKLNGVCMH HDLGALGAAV NYDATRRQLE
     KLKNMGVNAI RTSHNPPSRE LMELCDKMGF LVDSEIFDMW ELAKNENDYH RFFPDWYKKD
     VEAWIKRDRN HPSVIMWSIG NEIYDTHKSP RGLEVAKMLC EEVEKNDPMH NAPPTIASNY
     MQWENAQNVA DYLKLAGYNY TEKLYDEHHE KHPDWVIYGS ETASTVRSRG IYHFPYDTGL
     LVYDDLQCSD LGNSVVNWGA SPLRSFAMDA AAEYSMGQFV WTGFDYIGEP TPYNTKNSYF
     GIIDTAGFEK DSFWFYKSVW DIAEEESFIH VSPCCWDFNE GQLIDVLVYS DLPFIRLHYC
     GEMYDGKVID HLTEDKLCAR FKVPFHKNKP LAVRGYLSPD CDADDYEKET VLFTSLDPHS
     VNMTPDVSEI AADGRSLAFI TVTVDDIMGQ EVQNAVNRIK FTVKGAGRLV GLDNGDSTDY
     DSYKGNHRKL FSGKLLAIIE STFETGDIVI TAESEGLKPK TITIKAVAPE TEPQGVSVVT
     QNAFPAVTTP YTNEIPVRKI ELFDSEPRTL TKERDTAEIS VKIFPENATF RDIEFKCCTD
     NGVEISFAKV VSFDGNTATL KAFGDGKFRL RAYSKNGTDI PKIISELEYT AEGLGKAEKD
     PYIFIAACLC DFSNVPVITI DRGSLGGFNG RTTVGFSSVD FGGGTKKITI SVGNSGGGED
     YPVELYLGDA DNGGRYIGTF AIKNNGGWDR AYPQTFDLPC RISGTHDISF VINNSCIFGG
     FEFEKYDRTY AENSAADNDN LYGDDYKVNG SCVEEIGNNV VIEFNGLDFE GGTDKITVTG
     RTPLDNCTIQ LRVNDENGSQ TTRLLEFPHA DEYTPVTFDI EHIAGKNNIA FVFLPGTQFD
     MKSFRFTKTE D
//