ID   R6SIH4_9FIRM            Unreviewed;       367 AA.
AC   R6SIH4;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=Cobalamin-independent methionine synthase MetE C-terminal/archaeal domain-containing protein {ECO:0000259|Pfam:PF01717};
GN   ORFNames=BN586_01524 {ECO:0000313|EMBL:CDC55231.1};
OS   Dorea formicigenerans CAG:28.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX   NCBI_TaxID=1263073 {ECO:0000313|EMBL:CDC55231.1, ECO:0000313|Proteomes:UP000018109};
RN   [1] {ECO:0000313|EMBL:CDC55231.1, ECO:0000313|Proteomes:UP000018109}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:28 {ECO:0000313|Proteomes:UP000018109};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC55231.1}.
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DR   EMBL; CBFN010000075; CDC55231.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6SIH4; -.
DR   Proteomes; UP000018109; Unassembled WGS sequence.
DR   GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR   CDD; cd03311; CIMS_C_terminal_like; 1.
DR   Gene3D; 3.20.20.210; -; 1.
DR   InterPro; IPR002629; Met_Synth_C/arc.
DR   InterPro; IPR038071; UROD/MetE-like_sf.
DR   PANTHER; PTHR43844; METHIONINE SYNTHASE; 1.
DR   PANTHER; PTHR43844:SF1; METHIONINE SYNTHASE; 1.
DR   Pfam; PF01717; Meth_synt_2; 1.
DR   SUPFAM; SSF51726; UROD/MetE-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018109}.
FT   DOMAIN          9..343
FT                   /note="Cobalamin-independent methionine synthase MetE C-
FT                   terminal/archaeal"
FT                   /evidence="ECO:0000259|Pfam:PF01717"
SQ   SEQUENCE   367 AA;  42263 MW;  55BB8F2DD6BBCDAC CRC64;
     MIQIKYDIVG SFLRPEAIKK ARAEFKSGAI TREDLKKVED EEIAKLVKKE VEHGLSFITD
     GEFRRRWWHL DWLKEFDGFD TIHFTKEING TSNEIELGTV TGKIFYDKNK VHPEVEAWDY
     LHRLASQYEG VTAKKCISGP NMILIDHFLQ LGNKETPYYG RDLKALIDDI AKAYQEAILD
     FYDHGCRYLQ IDDTSWTYLI DEKFLQKVEA LGYTQKEVLN WFWNVSTKAL EKKPVDMVVA
     THFCKGNFKG NPLFSGFYDA VAPVIADIPY DAFFVEYDDA RSGSFEPWKV LKDKDALFVA
     GLISTKNPVL EDHDEIKKRY EEAKAVVGEQ IALSPQCGFA SVEEGNCIDE ETQWKKIDLL
     VSCKDFL
//