ID   R6TJ32_9LACO            Unreviewed;       660 AA.
AC   R6TJ32;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Putative capsular polysaccharide biosynthesis protein {ECO:0000313|EMBL:CDC58742.1};
GN   ORFNames=BN628_00016 {ECO:0000313|EMBL:CDC58742.1};
OS   Ligilactobacillus ruminis CAG:367.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Ligilactobacillus.
OX   NCBI_TaxID=1263085 {ECO:0000313|EMBL:CDC58742.1, ECO:0000313|Proteomes:UP000018129};
RN   [1] {ECO:0000313|EMBL:CDC58742.1, ECO:0000313|Proteomes:UP000018129}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:367 {ECO:0000313|Proteomes:UP000018129};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC58742.1}.
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DR   EMBL; CBFO010000105; CDC58742.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6TJ32; -.
DR   Proteomes; UP000018129; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        57..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        87..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          295..604
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   660 AA;  74363 MW;  A0112ED9010AA07B CRC64;
     MKNGSEKKFE HWKLISLYLV VYDIIAVNVS YFAALFLRFD MRISSIPPEC LHAFMKFAPF
     YTVFTLIVFH CLKLYNSLWQ FASFDELNRI IASSVVTTIF QGLFMTCLVT RMPASYYIFG
     AFIQFALIVG IRFSYRYINL ERNRRYNNHA AIHNVMVIGA GSAGKTILRE MRNSQGMTGK
     ACCVIDDNPN KWDRTMEGVP IVGGRDAILS AVKKYSIDQI MFAIPSASTE DKRDILNICK
     ETKCELKSLP GIYQLANGEV SLSKMKAVNV EDLLGRDPIK VDMAEVFRQL TGKTILVTGG
     GGSIGSELCR QIAAHNPKQL IIFDIYENNA YAIQQELVRK YGDKLNLVTL IGSVRDSRRL
     DMIFDKYRPD IVYHAAAHKH VPLMETSPNE AIKNNVVGTY KVAYMALKYD VERFVLISTD
     KAVNPTNIMG ASKRLCEMVI QSMERISENN DFDSLPLLHD HRKDGLKDVH PKTSRTKFVA
     VRFGNVLGSN GSVIPLFKKQ IAEGGPVTVT HPDIIRYFMT ISEAVSLVLQ AGTYAKGGEI
     FVLDMGSPVK IDTLARNLIK LSGYEPDVDI PIVYTGLRSG EKLYEEKLMK EEGLKKTANE
     LIFIGQPIPF DMDNFFRNLE DLSQASYQNS ADIVERVEKV VSTFHPVGDH PTGKEKIYQE
//