ID R6W0D0_9FIRM Unreviewed; 268 AA.
AC R6W0D0;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Short-chain dehydrogenase/reductase SDR {ECO:0000313|EMBL:CDD02840.1};
GN ORFNames=BN636_01309 {ECO:0000313|EMBL:CDD02840.1};
OS Ruminococcus sp. CAG:382.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1262957 {ECO:0000313|EMBL:CDD02840.1, ECO:0000313|Proteomes:UP000018166};
RN [1] {ECO:0000313|EMBL:CDD02840.1, ECO:0000313|Proteomes:UP000018166}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:382 {ECO:0000313|Proteomes:UP000018166};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484, ECO:0000256|RuleBase:RU000363}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD02840.1}.
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DR EMBL; CBGH010000145; CDD02840.1; -; Genomic_DNA.
DR AlphaFoldDB; R6W0D0; -.
DR STRING; 1262957.BN636_01309; -.
DR Proteomes; UP000018166; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
DR CDD; cd05233; SDR_c; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR44196; DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B; 1.
DR PANTHER; PTHR44196:SF5; POSSIBLE MULTI-FUNCTIONAL ENZYME WITH ACYL-COA-REDUCTASE ACTIVITY ACRA1; 1.
DR Pfam; PF00106; adh_short; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SMART; SM00822; PKS_KR; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023221};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000018166};
KW Steroid metabolism {ECO:0000256|ARBA:ARBA00023221}.
SQ SEQUENCE 268 AA; 29055 MW; 2BEACB3EC93514C7 CRC64;
MWLDGKTVII TGASGGLGFA MAKLLIEKHA CTVIGVARNR EKAEKAAAAL GDMFSFRLFD
VTDRTGWTSF ARELDESGLV PDVLINNAGI MPAFARAETC SDSDISAIVE TNFISYVTAV
RTLLPLLAKS ATPAVVNICS AGGLCPVVGE SMYCATKYAV RGFTDAFRAE HRRFYVAGIY
PGFIRTDIMR RQTVDVSQNS LIQSMMMPVD TAARRIVRAV GRRKNTCVIG VDGHLLSFFG
RVAPVPAVSV MERILRLSGQ ELFAFLGE
//
