ID R6XCR7_9FIRM Unreviewed; 304 AA.
AC R6XCR7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase {ECO:0000313|EMBL:CDD21443.1};
GN ORFNames=BN602_00448 {ECO:0000313|EMBL:CDD21443.1};
OS Firmicutes bacterium CAG:313.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263017 {ECO:0000313|EMBL:CDD21443.1, ECO:0000313|Proteomes:UP000018373};
RN [1] {ECO:0000313|EMBL:CDD21443.1, ECO:0000313|Proteomes:UP000018373}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:313 {ECO:0000313|Proteomes:UP000018373};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD21443.1}.
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DR EMBL; CBGQ010000017; CDD21443.1; -; Genomic_DNA.
DR AlphaFoldDB; R6XCR7; -.
DR STRING; 1263017.BN602_00448; -.
DR Proteomes; UP000018373; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0051745; F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0050992; P:dimethylallyl diphosphate biosynthetic process; IEA:InterPro.
DR GO; GO:0019288; P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; IEA:InterPro.
DR CDD; cd13944; lytB_ispH; 1.
DR Gene3D; 3.40.50.11270; -; 1.
DR Gene3D; 3.40.1010.20; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain; 2.
DR InterPro; IPR003451; LytB/IspH.
DR NCBIfam; TIGR00216; ispH_lytB; 1.
DR PANTHER; PTHR30426; 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR30426:SF0; 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE; 1.
DR Pfam; PF02401; LYTB; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018373}.
SQ SEQUENCE 304 AA; 34828 MW; 75DD5DB02A79C884 CRC64;
MRKIYISKNI GFCYGVSRAI KIVRDTITNK DLPRPIYLLG SLIHNHYINL YLKNNNVIVL
DGDTRDNLLN KIESGTVVFT AHGVSEAIKE KAINKCLNIV DATCPYVEKM FKAMEDKIKD
NYHIIFIGKK SHPESEVAMS FYPNVTLYDE NNLPDITGKI ALCHQTTMSS YDINEAYQIL
INKYPNIEKL DMLCKITENR QQELKLFKNN NVPTLIIVVG DSISNNSTKL YEMAKRINNV
DTIFVSSVNE LNLDDLKIYQ EIHLFSGTST PKAIVEEIYN VLNNLDNISK IKYESKLNLD
DYIK
//
