ID   R6XN51_9FIRM            Unreviewed;       230 AA.
AC   R6XN51;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   SubName: Full=2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2 {ECO:0000313|EMBL:CDD23050.1};
GN   ORFNames=BN617_00760 {ECO:0000313|EMBL:CDD23050.1};
OS   Firmicutes bacterium CAG:345.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1263020 {ECO:0000313|EMBL:CDD23050.1, ECO:0000313|Proteomes:UP000018232};
RN   [1] {ECO:0000313|EMBL:CDD23050.1, ECO:0000313|Proteomes:UP000018232}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:345 {ECO:0000313|Proteomes:UP000018232};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-
CC       erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
CC       {ECO:0000256|ARBA:ARBA00002459}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD23050.1}.
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DR   EMBL; CBGR010000022; CDD23050.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6XN51; -.
DR   STRING; 1263020.BN617_00760; -.
DR   Proteomes; UP000018232; Unassembled WGS sequence.
DR   GO; GO:0070567; F:cytidylyltransferase activity; IEA:InterPro.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR   CDD; cd02516; CDP-ME_synthetase; 1.
DR   InterPro; IPR034683; IspD/TarI.
DR   InterPro; IPR018294; ISPD_synthase_CS.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR32125; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR32125:SF4; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR   Pfam; PF01128; IspD; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR   PROSITE; PS01295; ISPD; 1.
PE   4: Predicted;
KW   Nucleotidyltransferase {ECO:0000313|EMBL:CDD23050.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018232};
KW   Transferase {ECO:0000313|EMBL:CDD23050.1}.
SQ   SEQUENCE   230 AA;  26532 MW;  E0B79F4D6091F53D CRC64;
     MNIAIILMAG KGERAETTIP KQYIIIDGKP IYEYCLLQFY RNKNIDKIIL VTDNIYYDKV
     KDYISLQKYD NKCEVTIGGK SRKESVLNAL IYLGNKIDKE DIVLVHDSAR PLVDETIIND
     NIKVASCNKI AVTAIKATST LVEIDTDNKS TKNYLDRSKI MEIQTPQSFK FSKFLKVSEY
     YREKSEQTDD SQIFFKAGEK LEFVKGNCFN FKITTMEDIK LFMTIMNSKM
//