ID R6YQ16_9BACT Unreviewed; 556 AA.
AC R6YQ16;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Xylosidase/arabinosidase {ECO:0000313|EMBL:CDD20452.1};
GN ORFNames=BN769_00530 {ECO:0000313|EMBL:CDD20452.1};
OS Prevotella sp. CAG:732.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1262934 {ECO:0000313|EMBL:CDD20452.1, ECO:0000313|Proteomes:UP000018039};
RN [1] {ECO:0000313|EMBL:CDD20452.1, ECO:0000313|Proteomes:UP000018039}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:732 {ECO:0000313|Proteomes:UP000018039};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD20452.1}.
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DR EMBL; CBGP010000135; CDD20452.1; -; Genomic_DNA.
DR AlphaFoldDB; R6YQ16; -.
DR Proteomes; UP000018039; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd18617; GH43_XynB-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF12; BETA-XYLOSIDASE-RELATED; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Reference proteome {ECO:0000313|Proteomes:UP000018039};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..556
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004437955"
FT DOMAIN 386..555
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT ACT_SITE 57
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 230
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 165
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 556 AA; 61937 MW; 2100DB3E66DF8C9D CRC64;
MKKLAILPLS CMLALGAHAQ TAEFDYFKYA GNDARFNVEI DKSHQYYNPV LAGFYPDPSL
CRVGDTYYLV NSSFTFFPGV PLSTSKDLVN WQPAGHVLDR PSQVPLKGQN VSGGIFAPAI
SYNKKNKTFY MITTNVGAGN FFVKSKDPSK GWSEPIYLPK IDGIDPSFFF DDNGKGYIVH
NGPVVGGADY EGQRAIRLFE FDVKGDSIKG DFKQILRGGT HVEAKPIWIE GPHLFKKDKY
YYLMCAEGGT GGWHSEVILR AKNPTGPWEE CPNNPILTQR TGLDPNRKDP VSSAGHADIV
EDGKGNWWAV FLACRPYEED MYNTGRDTYL LPVTWKNGWP EILAKNTPIA TVGEKAGLKP
AEKNEFSGNF SYTDNFEACD GKNGLKQLNS RWMFLRDFTD CYKVENGKLT LNLLPGNIYK
REPMSAIWAR QQHGTFTAET SLNFTPRNDK DIAGLALLQK EDHNFVLGKT MKNGKLMLTL
TRAEKNNVTI ASTPIKDGEL RLKVEGHGRY YDFFYAEQGG DWQLLAKGVD ASNLSTQKSG
GFIGAVIGLY ASSNKE
//
