ID   R6ZA57_9CLOT            Unreviewed;       508 AA.
AC   R6ZA57;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Arginine/lysine/ornithine decarboxylases {ECO:0000313|EMBL:CDD45263.1};
GN   ORFNames=BN593_00024 {ECO:0000313|EMBL:CDD45263.1};
OS   Clostridium sp. CAG:299.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262792 {ECO:0000313|EMBL:CDD45263.1, ECO:0000313|Proteomes:UP000017929};
RN   [1] {ECO:0000313|EMBL:CDD45263.1, ECO:0000313|Proteomes:UP000017929}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:299 {ECO:0000313|Proteomes:UP000017929};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC       {ECO:0000256|ARBA:ARBA00010671}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD45263.1}.
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DR   EMBL; CBGZ010000328; CDD45263.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6ZA57; -.
DR   STRING; 1262792.BN593_00024; -.
DR   Proteomes; UP000017929; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR   InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR   InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   PANTHER; PTHR43277; ARGININE DECARBOXYLASE; 1.
DR   PANTHER; PTHR43277:SF3; LYSINE DECARBOXYLASE; 1.
DR   Pfam; PF01276; OKR_DC_1; 1.
DR   Pfam; PF03711; OKR_DC_1_C; 1.
DR   SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017929}.
FT   DOMAIN          3..288
FT                   /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT                   attachment site"
FT                   /evidence="ECO:0000259|Pfam:PF01276"
FT   DOMAIN          433..481
FT                   /note="Orn/Lys/Arg decarboxylase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03711"
SQ   SEQUENCE   508 AA;  56384 MW;  6E03096F43E06B8F CRC64;
     MKLIDRLKEY GESDFYAFHM PGHKRQEELG ITLFPNPFSV DITEIDGFDN LHHPEGILKE
     SMERAAAVYG VDRTYYLVNG STCGILAAIS SAVSDGKKLL MARNSHKSAY HAAMLNRMET
     EYIYPEIIEE SGIQGGIEPG ELRRILEADK ENRIGAVFLT SPTYEGIVSD IKSLAEIAHE
     RGVPLIVDEA HGAHFAFYEG EGENRQTGRL FPRSALQCGA DLVIQSVHKT LPSLTQTAVL
     HLKEGITDRE RLEFYLRIYQ SSSPSYVMMA SIDNCIEYMA GEGRKRLEQL GRRLEHWMED
     AKQWSCLRVL DDHVLGENGA FDRDISKLVV GISPQAEKAG INGTALAEAV RRRFHLEPEM
     CCDRYVLYMT SLMDSEESLF KLSAALTKID EEIAGALCMG RNEGTEGTSE ETEKYSGKQG
     TLTWTRDVPR RISMAEAVSK KGRRIRLEDA CGCISRGFLT VYPPGVPAVV PGEMISQETA
     ELLLKNAGLG LTVEGLDSDG SIDAVKDE
//