ID   R7A089_9FIRM            Unreviewed;       365 AA.
AC   R7A089;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=KHG/KDPG family aldolase/carbohydrate kinase PfkB family {ECO:0000313|EMBL:CDD36162.1};
GN   ORFNames=BN600_00307 {ECO:0000313|EMBL:CDD36162.1};
OS   Roseburia sp. CAG:309.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=1262945 {ECO:0000313|EMBL:CDD36162.1, ECO:0000313|Proteomes:UP000018292};
RN   [1] {ECO:0000313|EMBL:CDD36162.1, ECO:0000313|Proteomes:UP000018292}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:309 {ECO:0000313|Proteomes:UP000018292};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD36162.1}.
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DR   EMBL; CBGX010000365; CDD36162.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7A089; -.
DR   STRING; 1262945.BN600_00307; -.
DR   Proteomes; UP000018292; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd01166; KdgK; 1.
DR   Gene3D; 3.40.1190.20; -; 1.
DR   InterPro; IPR011611; PfkB_dom.
DR   InterPro; IPR029056; Ribokinase-like.
DR   PANTHER; PTHR43320:SF2; 2-DEHYDRO-3-DEOXYGLUCONOKINASE_2-DEHYDRO-3-DEOXYGALACTONOKINASE; 1.
DR   PANTHER; PTHR43320; SUGAR KINASE; 1.
DR   Pfam; PF00294; PfkB; 1.
DR   SUPFAM; SSF53613; Ribokinase-like; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CDD36162.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018292};
KW   Transferase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CDD36162.1}.
FT   DOMAIN          15..347
FT                   /note="Carbohydrate kinase PfkB"
FT                   /evidence="ECO:0000259|Pfam:PF00294"
SQ   SEQUENCE   365 AA;  39758 MW;  802D8B42CBF100B4 CRC64;
     MNLNLRPAEE CKYDAVSLGE VMLRLDPGEG RIRTARSFRA WEGGGEYNVV RGLRRCFGMN
     TGVITAFADN EVGKLMEDFI LQGGVDTSLI KWMETDGIGR VCRNGLNFTE RGFGIRGAVG
     CSDRANTAIS KAKPEDFDFD YIFSELGARW LHTGGIYAAL SEQSCETVLA AIKAAKKYGT
     IVSYDLNYRP SMWSAIGGIE KAQEVNKEIA KYVDVMIGNE EDFTACLGFE IEGNDADLKE
     LNLDGYKKMI NEAAKTYPNF KAVATTLREV KTATVNDWSA ICWADGEIFK AKDYKGLEIM
     DRVGGGDSFA SGLIYGLMTT ENAELAVNYG AAHGALAMTT PGDTTMASKK EVEAIMGGAG
     ARVQR
//