ID   R7A269_9BACE            Unreviewed;       655 AA.
AC   R7A269;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=Glycosyl hydrolase {ECO:0000313|EMBL:CDD49634.1};
GN   ORFNames=BN800_00138 {ECO:0000313|EMBL:CDD49634.1};
OS   Bacteroides sp. CAG:875.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1262752 {ECO:0000313|EMBL:CDD49634.1, ECO:0000313|Proteomes:UP000018287};
RN   [1] {ECO:0000313|EMBL:CDD49634.1, ECO:0000313|Proteomes:UP000018287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:875 {ECO:0000313|Proteomes:UP000018287};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC       {ECO:0000256|ARBA:ARBA00006285}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD49634.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CBHD010000101; CDD49634.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7A269; -.
DR   Proteomes; UP000018287; Unassembled WGS sequence.
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd06564; GH20_DspB_LnbB-like; 1.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR   InterPro; IPR015883; Glyco_hydro_20_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR015882; HEX_bac_N.
DR   PANTHER; PTHR43678:SF1; BETA-N-ACETYLHEXOSAMINIDASE; 1.
DR   PANTHER; PTHR43678; PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00640)-RELATED; 1.
DR   Pfam; PF00728; Glyco_hydro_20; 1.
DR   Pfam; PF02838; Glyco_hydro_20b; 1.
DR   PRINTS; PR00738; GLHYDRLASE20.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CDD49634.1};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..655
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004427578"
FT   DOMAIN          28..151
FT                   /note="Beta-hexosaminidase bacterial type N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02838"
FT   DOMAIN          155..474
FT                   /note="Glycoside hydrolase family 20 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00728"
FT   ACT_SITE        316
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ   SEQUENCE   655 AA;  75085 MW;  20D3E35C649AEA22 CRC64;
     MRILKKIVLL AYSVCCLSGA VWAQNVKPFV IPELKEWKGG DGQFTPTASS RIVCTSGETE
     LLRVVQAFAA DYEEMFGVYM PVSVGKSTAG DFVFQLKPDR KMPKEGYDIR ITDRVLVSAP
     ETSGAFWATR TLLQMTEQSD TRSLSKGTMR DFPSYAVRGF MFDCARKFFT IDFLRDYVKF
     MAYYKMNTLQ LHLNDNGFKQ YFDNDWNKTY AAFRLECDTY SGLTAEDGFY TKQQFIDLQK
     LAENNYVEII PEIDAPAHSL AFTHYKPEIG SQTYGMDHLD LGNPETYKFM DGLFKEYLEG
     DNPVFRGKRV NIGTDEYSNK DKKVVEQFRA FTDHYIKYVE KYGKQACAWG ALTHAQGDTP
     VKVDNVILNL WYNNYAQPRE MKKLGYKMIC IPDGLVYIVP QAGYYNDYLN CQYLYENWTP
     AIIGDEVFDE KDPSILGGMF AVWNDHVGNG ISMQDVHHRV FPAMQTMAVK MWTGKDTKLP
     YAEFNQKRIT LSEAPGVNIL GRIGSGKELV YETDVVYPNM KTPHREIGYD YTVSFDIEGT
     NETKGTELFR SRDAVFYLSD PLSGMLGYAR DGYLYTFDYR VKPGKTNLAI EGDSQSTRLY
     VNGKLVEELG KQTLYYNEGG KDKMYRSCTL VFPLEQAGKF SSRINNLKIY NYKQH
//