ID R7C1M1_9BURK Unreviewed; 791 AA.
AC R7C1M1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Anaerobic dimethyl sulfoxide reductase chain A {ECO:0000313|EMBL:CDD72034.1};
GN ORFNames=BN641_00349 {ECO:0000313|EMBL:CDD72034.1};
OS Sutterella sp. CAG:397.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sutterellaceae; Sutterella.
OX NCBI_TaxID=1262976 {ECO:0000313|EMBL:CDD72034.1, ECO:0000313|Proteomes:UP000018105};
RN [1] {ECO:0000313|EMBL:CDD72034.1, ECO:0000313|Proteomes:UP000018105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:397 {ECO:0000313|Proteomes:UP000018105};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD72034.1}.
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DR EMBL; CBHO010000167; CDD72034.1; -; Genomic_DNA.
DR AlphaFoldDB; R7C1M1; -.
DR Proteomes; UP000018105; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0009389; F:dimethyl sulfoxide reductase activity; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR CDD; cd02794; MopB_CT_DmsA-EC; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.12440; -; 2.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR011888; Anaer_DMSO_reductase.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006311; TAT_signal.
DR NCBIfam; TIGR02166; dmsA_ynfE; 1.
DR PANTHER; PTHR43742:SF3; DIMETHYL SULFOXIDE REDUCTASE DMSA; 1.
DR PANTHER; PTHR43742; TRIMETHYLAMINE-N-OXIDE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000018105};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..791
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004428723"
FT DOMAIN 37..98
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 791 AA; 87930 MW; 322A37548E33BC66 CRC64;
MLFHSVSRRS LLQGLALSGL AAAPVSKAVS AALADYENYK WCACVINCGQ RCALRCFTKN
GQVIRIETDN TQPDTLGPRQ LRACQRGRSM RERLYCPDRL KFPMKRVGKR GEGKFVRISW
EEAVDTIAKE WTRIRDTYGN DAIYWQYCSG QQSLVSSRRA WQRLMNLMGG FLKYYGSYSN
AQGAASFPLT YGGRPSSLPS EIANAELYVL FGNNPSVTRP SGGGKGFQID AAFAKHKPRM
IVIDPCFTDT CTSRADQWVP IRPGTDAALV GALAYEFITK NWVDQAFLDT YCVGYDEKTL
PASAPKGSDY KSYILGKGPD KTAKTPQWAS KITGIPADVI TDLARQMATT KPLFVSQGWG
PQRQANGEET CRAIAMVPIL LGQVGLSGTS TGAHEGNTSF PAVYLPVGKN PVKATIPVYL
WTDAILRGKE MTRQTDALKG VEKLTADIKM IVNSGGNTMI NQHGDCNWTD KVLQDTKKCE
FIVVCDNMMT PSCRYADILL PDTLGPETDD MACQGGSHGD VAAMLAIQKA VEPQFEQKTS
WEICRLIAAK LGLEEKFTEG KTQMEWVRWC YEETRKKVPE LPAFEAFWKA GVAKVWNYRK
DPIALEAFRK DPEKNKLKTP SGKIEIYSER LAKETADWKL ADGDVISPIP VFWRSWDMPG
DTLAKKYPLQ CFGFHGHGRI HSTFHNLPKL RYMHPDMVVM NPVDADARGV KDGDKVMVFN
DRGRLMLPAR VTPRIMPGVI TIPQGAWFDP KVIDGKRVDV GGCINTLTAH RPSPYAKGNA
QHNILVEVRK A
//
